Tag Archives: Stress

University of Illinois Chicago study: One-third of US adults may unknowingly use medications that can cause depression

17 Jun

Moi said in Schools have to deal with depressed and troubled children:
Both the culture and the economy are experiencing turmoil. For some communities, the unsettled environment is a new phenomenon, for other communities, children have been stressed for generations. According to the article, Understanding Depression which was posted at the Kids Health site:

Depression is the most common mental health problem in the United States. Each year it affects 17 million people of all age groups, races, and economic backgrounds.
As many as 1 in every 33 children may have depression; in teens, that number may be as high as 1 in 8. http://kidshealth.org/parent/emotions/feelings/understanding_depression.html

Schools are developing strategies to deal with troubled kids.

Anna M. Phillips wrote the New York Times article, Calming Schools by Focusing on Well-Being of Troubled Students which describes how one New York school is dealing with its troubled children.

Mark Ossenheimer, principal of the Urban Assembly School for Wildlife Conservation in the Bronx, threw out a name to add to the list of teenagers in trouble.
Several teachers and a social worker seated around a table in the school’s cramped administrative offices nodded in agreement. They had watched the student, who had a housebound parent who was seriously ill, sink into heavy depression. Another child seemed to be moving from apartment to apartment, showing up at school only sporadically. And then there was the one grappling with gender-identity issues. Soon the list had a dozen names of students who could shatter a classroom’s composure or a school windowpane in a second.
Convening the meeting was Turnaround for Children, a nonprofit organization that the young-but-faltering school in an impoverished neighborhood near the Bronx Zoo had brought in this year to try to change things.
“This is the condition our organization was created to solve,” said Dr. Pamela Cantor, Turnaround’s founder and president. “A teacher who works in a community like this and thinks that these children can leave their issues at the door and come in and perform is dreaming.”
In focusing on students’ psychological and emotional well-being, in addition to academics, Turnaround occupies a middle ground between the educators and politicians who believe schools should be more like community centers, and the education-reform movement, with its no-excuses mantra. Over the past decade, the movement has argued that schools should concentrate on what high-quality, well-trained teachers can achieve in classrooms, rather than on the sociological challenges beyond their doors. http://www.nytimes.com/2011/11/15/nyregion/calming-schools-through-a-sociological-approach-to-troubled-students.html?hpw

One strategy in helping children to succeed is to recognize and treat depression. https://drwilda.com/2011/11/15/schools-have-to-deal-with-depressed-and-troubled-children/

Science Daily reported in One-third of US adults may unknowingly use medications that can cause depression:

A new study from University of Illinois at Chicago researchers suggests that more than one-third of U.S. adults may be using prescription medications that have the potential to cause depression or increase the risk of suicide, and that because these medications are common and often have nothing to do with depression, patients and health care providers may be unaware of the risk.
The researchers retrospectively analyzed medication use patterns of more than 26,000 adults from 2005 to 2014, which were collected as part of the National Health and Nutrition Examination Survey. They found that more than 200 commonly used prescription drugs — including hormonal birth control medications, blood pressure and heart medications, proton pump inhibitors, antacids and painkillers — have depression or suicide listed as potential side effects.
Published in the Journal of the American Medical Association, the study is the first to demonstrate that these drugs were often used concurrently and that concurrent use, called polypharmacy, was associated with a greater likelihood of experiencing depression. Approximately 15 percent of adults who simultaneously used three or more of these medications experienced depression while taking the drugs, compared with just 5 percent for those not using any of the drugs, 7 percent for those using one medication and 9 percent for those taking two drugs simultaneously.
The researchers observed similar results for drugs that listed suicide as a potential side effect. These findings persisted when the researchers excluded anyone using psychotropic medications, considered an indicator of underlying depression unrelated to medication use.
“The take away message of this study is that polypharmacy can lead to depressive symptoms and that patients and health care providers need to be aware of the risk of depression that comes with all kinds of common prescription drugs — many of which are also available over the counter,” said lead author Dima Qato, assistant professor of pharmacy systems, outcomes and policy in the UIC College of Pharmacy. “Many may be surprised to learn that their medications, despite having nothing to do with mood or anxiety or any other condition normally associated with depression, can increase their risk of experiencing depressive symptoms, and may lead to a depression diagnosis.”
Qato notes that the study also shows an important trend of increasing polypharmacy for medications with depression, particularly suicidal symptoms, as a potential adverse effect. This makes the need for awareness of depression as a potential side effect even more pressing…. https://www.sciencedaily.com/releases/2018/06/180612185204.htm

Citation:

One-third of US adults may unknowingly use medications that can cause depression
Polypharmacy on the rise
Date: June 12, 2018
Source: University of Illinois at Chicago
Summary:
A new study suggests that more than one-third of U.S. adults may be using prescription medications that have the potential to cause depression or increase the risk of suicide.

Journal Reference:
1. Dima Mazen Qato, Katharine Ozenberger, Mark Olfson. Prevalence of Prescription Medications With Depression as a Potential Adverse Effect Among Adults in the United States. JAMA, 2018; 319 (22): 2289 DOI: 10.1001/jama.2018.6741

Here is the press release from University of Illinois Chicago:

One-third of US adults may unknowingly use medications that can cause depression
June 12, 2018
A new study from University of Illinois at Chicago researchers suggests that more than one-third of U.S. adults may be using prescription medications that have the potential to cause depression or increase the risk of suicide, and that because these medications are common and often have nothing to do with depression, patients and health care providers may be unaware of the risk.
The researchers retrospectively analyzed medication use patterns of more than 26,000 adults from 2005 to 2014, which were collected as part of the National Health and Nutrition Examination Survey. They found that more than 200 commonly used prescription drugs — including hormonal birth control medications, blood pressure and heart medications, proton pump inhibitors, antacids and painkillers — have depression or suicide listed as potential side effects.
Published in the Journal of the American Medical Association, the study is the first to demonstrate that these drugs were often used concurrently and that concurrent use, called polypharmacy, was associated with a greater likelihood of experiencing depression. Approximately 15 percent of adults who simultaneously used three or more of these medications experienced depression while taking the drugs, compared with just 5 percent for those not using any of the drugs, 7 percent for those using one medication and 9 percent for those taking two drugs simultaneously.
The researchers observed similar results for drugs that listed suicide as a potential side effect. These findings persisted when the researchers excluded anyone using psychotropic medications, considered an indicator of underlying depression unrelated to medication use.
“The take away message of this study is that polypharmacy can lead to depressive symptoms and that patients and health care providers need to be aware of the risk of depression that comes with all kinds of common prescription drugs — many of which are also available over the counter,” said lead author Dima Qato, assistant professor of pharmacy systems, outcomes and policy in the UIC College of Pharmacy. “Many may be surprised to learn that their medications, despite having nothing to do with mood or anxiety or any other condition normally associated with depression, can increase their risk of experiencing depressive symptoms, and may lead to a depression diagnosis.”
Qato notes that the study also shows an important trend of increasing polypharmacy for medications with depression, particularly suicidal symptoms, as a potential adverse effect. This makes the need for awareness of depression as a potential side effect even more pressing.
The researchers found use of any prescription medication with a potential depression adverse effect increased from 35 percent in the 2005 to 2006 period to 38 percent in the 2013 to 2014 period. Approximate use of antacids with potential depression adverse effects, like proton pump inhibitors and H2 antagonists, increased from 5 percent to 10 percent in the same period. Use of three or more drugs concurrently increased from 7 percent to 10 percent, approximately.
For prescription drugs with suicide listed as a potential side effect, usage increased from 17 percent to 24 percent, and use of three or more drugs concurrently increased from 2 percent to 3 percent.
“People are not only increasingly using these medicines alone, but are increasingly using them simultaneously, yet very few of these drugs have warning labels, so until we have public or system-level solutions, it is left up to patients and health care professionals to be aware of the risks,” Qato said.
Qato says that solutions worth further study may include updating drug safety software to recognize depression as a potential drug-drug interaction, so that health care professionals, including pharmacists, are more likely to notice if a patient is using multiple medications that may increase risk. Or, including evaluation of medication use in the depression screening and diagnostic tools used by doctors and nurses and recommended by the U.S. Preventive Services Task Force, especially when it comes to persistent or treatment-resistant depression.
“With depression as one of the leading causes of disability and increasing national suicide rates, we need to think innovatively about depression as a public health issue, and this study provides evidence that patterns of medication use should be considered in strategies that seek to eliminate, reduce or minimize the impact of depression in our daily lives,” Qato said.
Co-authors on the study are Katharine Ozenberger of UIC and Columbia University’s Mark Olfson. Qato and Olfson both noted financial disclosures potentially relevant to the study.
Contact
Jacqueline Carey
312-996-8277
jmcarey@uic.edu
twitter.com/JCareyUIC

If you or your child needs help for depression or another illness, then go to a reputable medical provider. There is nothing wrong with taking the steps necessary to get well.

Related:

Schools have to deal with depressed and troubled children
https://drwilda.wordpress.com/2011/11/15/schools-have-to-deal-with-depressed-and-troubled-children/

School psychologists are needed to treat troubled children
https://drwilda.wordpress.com/2012/02/27/school-psychologists-are-needed-to-treat-troubled-children/

Battling teen addiction: ‘Recovery high schools’
https://drwilda.wordpress.com/2012/07/08/battling-teen-addiction-recovery-high-schools/

Resources:
1. About.Com’s Depression In Young Children http://depression.about.com/od/child/Young_Children.htm

2. Psych Central’s Depression In Young Children http://depression.about.com/od/child/Young_Children.htm

3. Psychiatric News’ Study Helps Pinpoint Children With Depression http://psychnews.psychiatryonline.org/newsarticle.aspx?articleid=106034

4. Family Doctor’s What Is Depression? http://familydoctor.org/familydoctor/en/diseases-conditions/depression.html

5. WebMD’s Depression In Children http://www.webmd.com/depression/guide/depression-children

6. Healthline’s Is Your Child Depressed?
http://www.healthline.com/hlvideo-5min/how-to-help-your-child-through-depression-517095449

7. Medicine.Net’s Depression In Children http://www.onhealth.com/depression_in_children/article.htm

Where information leads to Hope. © Dr. Wilda.com

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Blogs by Dr. Wilda:

COMMENTS FROM AN OLD FART©
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Dr. Wilda Reviews ©
http://drwildareviews.wordpress.com/

Dr. Wilda ©
https://drwilda.com/

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Drexel University study: Trauma from parents’ youth linked to poorer health, asthma in their own children

10 Jun

Moi reported about the effect stress has on genes in Penn State study: Stress alters children’s genomes https://drwilda.com/2014/04/08/penn-state-study-stress-alters-childrens-genomes/ A Tulane Medical School study finds that family violence or trauma alters a child’s genomes.

Science Daily reported in the article, Family violence leaves genetic imprint on children:

A new Tulane University School of Medicine study finds that the more fractured families are by domestic violence or trauma, the more likely that children will bear the scars down to their DNA.
Researchers discovered that children in homes affected by domestic violence, suicide or the incarceration of a family member have significantly shorter telomeres, which is a cellular marker of aging, than those in stable households. The findings are published online in the latest issue of the journal Pediatrics.
Telomeres are the caps at the end of chromosomes that keep them from shrinking when cells replicate. Shorter telomeres are linked to higher risks for heart disease, obesity, cognitive decline, diabetes, mental illness and poor health outcomes in adulthood. Researchers took genetic samples from 80 children ages 5 to 15 in New Orleans and interviewed parents about their home environments and exposures to adverse life events….
The study found that gender moderated the impact of family instability. Traumatic family events were more detrimental to young girls as they were more likely to have shortened telomeres. There was also a surprising protective effect for boys: mothers who had achieved a higher level of education had a positive association with telomere length, but only in boys under 10.
Ultimately, the study suggests that the home environment is an important intervention target to reduce the biological impacts of adversity in the lives of young children, Drury said. http://www.sciencedaily.com/releases/2014/06/140617102505.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29&utm_content=FaceBook

See, https://drwilda.com/tag/stress/

Science Daily reported in Trauma from parents’ youth linked to poorer health, asthma in their own children:

Trauma experienced by a parent during childhood has long-reaching consequences — maybe even to the point of negatively impacting their own children’s health, a new Drexel University study found.
“It is well known that adverse childhood experiences can lead to serious and wide-ranging effects on the health of the people who go through them,” said Félice Lê-Scherban, PhD, the study’s lead researcher and an assistant professor in Drexel’s Dornsife School of Public Health. “A lot of these health problems — such as substance abuse, depression or chronic illnesses like cardiovascular disease — can affect how parents care for their kids and the environments where they grow up.”
“Adverse childhood experiences” are described as serious traumas or stress a person experiences during their formative years. This might include something like abuse or exposure to violence and/or drugs. The study, published in Pediatrics, looked into surveys taken by 350 Philadelphia parents who answered questions about their own “ACEs.”
It found that for every type of “ACE” a parent went through, their children had 19 percent higher odds of poorer health and 17 percent higher odds of having asthma.
“If we only look at the within-individual effects of ACEs, we may be underestimating their lasting impact on health across multiple generations,” Lê-Scherban said of the study team’s motivations. “Looking intergenerationally gives us a more comprehensive picture of the long-term processes that might affect children’s health.”
“By the same token, acting to prevent ACEs and helping those who have experienced them can potentially have benefits extending to future generations,” Lê-Scherban added.
Among the parents who were surveyed:
— Nearly 42 percent said they’d witnessed violence (seeing someone shot, stabbed or beaten) as a child
— 38 percent said they lived with a problem drinker or someone who used illicit drugs during their youth
— Roughly 37 percent said that they had been physically abused as children
While those were the most common ACEs, there were many others that received strong responses, including experiencing racial discrimination and sexual abuse.
Overall, 85 percent of parents experienced at least one ACE. The more ACEs a parent had suffered as a child, the more likely their own children were to have poorer health status.
One of the other areas that Lê-Scherban and her fellow researchers focused on was behavior in the survey respondents’ children that could have an impact on health. They found that each ACE a parent had experienced was tied to an additional 16 percent higher odds that their children would have excessive TV-watching habits. While not a direct health outcome, it sets up a child for potentially poorer health habits down the line.
And though ACEs are more prevalent in populations low on the socioeconomic scale, that doesn’t explain everything, Lê-Scherban said…. https://www.sciencedaily.com/releases/2018/06/180604172745.htm

Citation:

Trauma from parents’ youth linked to poorer health, asthma in their own children
Date: June 4, 2018
Source: Drexel University
Summary:
A new study found that for each type of adverse childhood experience a parent went through, their children had 19 percent higher odds of poorer health.
Journal Reference:
1. Félice Lê-Scherban, Xi Wang, Kathryn H. Boyle-Steed, Lee M. Pachter. Intergenerational Associations of Parent Adverse Childhood Experiences and Child Health Outcomes. Pediatrics, 2018; 141 (6): e20174274 DOI: 10.1542/peds.2017-4274

Here is the press release from Drexel University:

Trauma from Parents’ Youth Linked to Poorer Health, Asthma in Their Own Children
By: Frank Otto
June 4, 2018

Trauma experienced by a parent during childhood has long-reaching consequences — maybe even to the point of negatively impacting their own children’s health, a new Drexel University study found.
“It is well known that adverse childhood experiences can lead to serious and wide-ranging effects on the health of the people who go through them,” said Félice Lê-Scherban, PhD, the study’s lead researcher and an assistant professor in Drexel’s Dornsife School of Public Health. “A lot of these health problems — such as substance abuse, depression or chronic illnesses like cardiovascular disease — can affect how parents care for their kids and the environments where they grow up.”
“Adverse childhood experiences” are described as serious traumas or stress a person experiences during their formative years. This might include something like abuse or exposure to violence and/or drugs. The study, published in Pediatrics, looked into surveys taken by 350 Philadelphia parents who answered questions about their own “ACEs.”
It found that for every type of “ACE” a parent went through, their children had 19 percent higher odds of poorer health and 17 percent higher odds of having asthma.
“If we only look at the within-individual effects of ACEs, we may be underestimating their lasting impact on health across multiple generations,” said Lê-Scherban — who also serves as a researcher in her school’s Urban Health Collaborative — about the study team’s motivations. “Looking intergenerationally gives us a more comprehensive picture of the long-term processes that might affect children’s health.”
“By the same token, acting to prevent ACEs and helping those who have experienced them can potentially have benefits extending to future generations,” Lê-Scherban added.
Among the parents who were surveyed:
• Nearly 42 percent said they’d witnessed violence (seeing someone shot, stabbed or beaten) as a child
• 38 percent said they lived with a problem drinker or someone who used illicit drugs during their youth
• Roughly 37 percent said that they had been physically abused as children
While those were the most common ACEs, there were many others that received strong responses, including experiencing racial discrimination and sexual abuse.
Overall, 85 percent of parents experienced at least one ACE. The more ACEs a parent had suffered as a child, the more likely their own children were to have poorer health status.
One of the other areas that Lê-Scherban and her fellow researchers focused on was behavior in the survey respondents’ children that could have an impact on health. They found that each ACE a parent had experienced was tied to an additional 16 percent higher odds that their children would have excessive TV-watching habits. While not a direct health outcome, it sets up a child for potentially poorer health habits down the line.
And though ACEs are more prevalent in populations low on the socioeconomic scale, that doesn’t explain everything, Lê-Scherban said.
“It’s important to remember that ACEs, and their effects, occur across the socioeconomic spectrum,” Lê-Scherban commented.
While the links can’t be definitively established as causal yet, they suggest that it’s important to keep studying the multigenerational effects that trauma has on health, according to Lê-Scherban.
“We need to know more about the specific pathways through which parental ACEs might harm child health so we can minimize these harms,” she said. “On the flip side, it’s important to learn more about the factors that promote resilience to help parents and their children thrive despite past trauma.”
Those interested in reading the full study, “Intergenerational Associations of Parent Adverse Childhood Experiences and Child Health Outcomes,” can access it here.
Media Contact:
Frank Otto
fmo26@drexel.edu
215.571.4244

Here is information about the Adverse Child Experiences Study. The Centers for Disease Control and Prevention provides access to the peer-reviewed publications resulting from The ACE Study. http://acestudy.org/
https://drwilda.com/2012/11/09/study-some-of-the-effects-of-adverse-stress-do-not-go-away/

Science Daily reported in Infantile memory study points to critical periods in early-life learning for brain development:

A new study on infantile memory formation in rats points to the importance of critical periods in early-life learning on functional development of the brain. The research, conducted by scientists at New York University’s Center for Neural Science, reveals the significance of learning experiences over the first two to four years of human life; this is when memories are believed to be quickly forgotten — a phenomenon known as infantile amnesia.
“What our findings tell us is that children’s brains need to get enough and healthy activation even before they enter pre-school,” explains Cristina Alberini, a professor in NYU’s Center for Neural Science, who led the study. “Without this, the neurological system runs the risk of not properly developing learning and memory functions…”
https://www.sciencedaily.com/releases/2016/07/160718111939.htm

Citation:

Infantile memory study points to critical periods in early-life learning for brain development
Date: July 18, 2016
Source: New York University
Summary:
A new study on infantile memory formation in rats points to the importance of critical periods in early-life learning on functional development of the brain. The research reveals the significance of learning experiences over the first two to four years of human life.
Journal Reference:
1. Alessio Travaglia, Reto Bisaz, Eric S Sweet, Robert D Blitzer, Cristina M Alberini. Infantile amnesia reflects a developmental critical period for hippocampal learning. Nature Neuroscience, 2016; DOI: 10.1038/nn.4348

Our goal as a society should be:
A healthy child in a healthy family who attends a healthy school in a healthy neighborhood ©

Resources:

The Effects of Stress on Your Body
http://www.webmd.com/mental-health/effects-of-stress-on-your-body

The Physical Effects of Long-Term Stress
http://psychcentral.com/lib/2007/the-physical-effects-of-long-term-stress/all/1/

Chronic Stress: The Body Connection
http://www.medicinenet.com/script/main/art.asp?articlekey=53737

Understanding Stress Symptoms, Signs, Causes, and Effects
http://www.helpguide.org/mental/stress_signs.htm

Dr. Wilda says this about that ©

Blogs by Dr. Wilda:

COMMENTS FROM AN OLD FART ©
http://drwildaoldfart.wordpress.com/

Dr. Wilda Reviews ©
http://drwildareviews.wordpress.com/

Dr. Wilda ©
https://drwilda.com/

Dartmouth College study: Humans and others exposed to prenatal stress have high stress levels after birth

15 Apr

Moi reported about the effect stress has on genes in Penn State study: Stress alters children’s genomes https://drwilda.com/2014/04/08/penn-state-study-stress-alters-childrens-genomes/ A Tulane Medical School study finds that family violence or trauma alters a child’s genomes.

Science Daily reported in the article, Family violence leaves genetic imprint on children:

A new Tulane University School of Medicine study finds that the more fractured families are by domestic violence or trauma, the more likely that children will bear the scars down to their DNA.
Researchers discovered that children in homes affected by domestic violence, suicide or the incarceration of a family member have significantly shorter telomeres, which is a cellular marker of aging, than those in stable households. The findings are published online in the latest issue of the journal Pediatrics.
Telomeres are the caps at the end of chromosomes that keep them from shrinking when cells replicate. Shorter telomeres are linked to higher risks for heart disease, obesity, cognitive decline, diabetes, mental illness and poor health outcomes in adulthood. Researchers took genetic samples from 80 children ages 5 to 15 in New Orleans and interviewed parents about their home environments and exposures to adverse life events….
The study found that gender moderated the impact of family instability. Traumatic family events were more detrimental to young girls as they were more likely to have shortened telomeres. There was also a surprising protective effect for boys: mothers who had achieved a higher level of education had a positive association with telomere length, but only in boys under 10.
Ultimately, the study suggests that the home environment is an important intervention target to reduce the biological impacts of adversity in the lives of young children, Drury said. http://www.sciencedaily.com/releases/2014/06/140617102505.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29&utm_content=FaceBook

See, https://drwilda.com/tag/stress/

Science Daily reported in Humans and others exposed to prenatal stress have high stress levels after birth:

Vertebrate species, including humans, exposed to stress prenatally tend to have higher stress hormones after birth, according to a new Dartmouth-led study published in Scientific Reports. While previous research has reported examples of maternal stress experience predicting offspring stress hormones in different species, this study is the first to empirically demonstrate the impact of prenatal stress on offspring stress hormone levels using data from all known studies across vertebrates.
Through a meta-analysis of 114 results from a total of 39 observational and experimental studies across 14 vertebrate species, including birds, snakes, sheep and humans, the study examines the impact of prenatal exposure to maternal stress on offspring. The researchers analyzed the role of the hypothalamic pituitary adrenal (HPA)-axis, the stress physiological system that is shared across all vertebrates, which ultimately, results in the production of stress hormones known as “glucocorticoids.” The HPA-axis is the hormonal system responsible for mobilizing an animal’s stress response. Offspring exposed prenatally to maternal stress were found to have more stress hormone levels (glucocorticoids) after birth. This could reflect a biological adaptation with an evolutionary history, as more stress hormones could increase an animal’s chances for survival in a stressful environment.
In the present study, the researchers tested the strength of the effect of prenatal stress on offspring stress hormone levels across a range of characteristics. Remarkably, the effects of prenatal stress on offspring stress hormones were consistent across species, regardless of evolutionary relationships or factors, such as brain or body size. There were also no differences when considering offspring sex, age of the offspring at the time of assessment, or the timing of the stressor exposure prenatally or its severity.
Only two factors influenced the size of the effect. Experimental studies had a stronger effect than observational studies. In addition, studies that measured glucocorticoid recovery showed a greater association with prenatal stress than was observed at baseline or during peak glucocorticoid response….
An animal’s stress response tends to be activated by external factors, such as when its see a predator or whether food is availabile. Higher stress hormone levels among offspring may help extend survival but come at a cost and may affect other physiological systems, such as reproduction. In humans, the mere anticipation of stress or just thinking about prior experiences of discrimination or trauma can activate a stress response. Overactive stress hormones can lead to chronic health problems in humans, including anxiety, depression and cardiovascular disease.
One of the studies included in the meta-analysis looked at how maternal stress hormones in pregnant snow hares changed in relation to the abundance of their natural predators, lynxes, over a 10-year cycle. The research team found that in years where there were more lynxes, snow hare offspring had more stress hormones and anti-predator behaviors….’’ https://www.sciencedaily.com/releases/2018/04/180410161135.htm

Citation:

Humans and others exposed to prenatal stress have high stress levels after birth
Date: April 10, 2018
Source: Dartmouth College
Summary:
Vertebrate species, including humans, exposed to stress prenatally tend to have higher stress hormones after birth, according to a new study. While previous research has reported examples of maternal stress experience predicting offspring stress hormones in different species, this study is the first to empirically demonstrate the impact of prenatal stress on offspring stress hormone levels using data from all known studies across vertebrates.

Journal Reference:
1. Zaneta M. Thayer, Meredith A. Wilson, Andrew W. Kim, Adrian V. Jaeggi. Impact of prenatal stress on offspring glucocorticoid levels: A phylogenetic meta-analysis across 14 vertebrate species. Scientific Reports, 2018; 8 (1) DOI: 10.1038/s41598-018-23169-w

Here is the press release from Dartmouth College:

Public Release: 10-Apr-2018
Study finds humans and others exposed to prenatal stress have high stress levels after birth
Dartmouth College
Vertebrate species, including humans, exposed to stress prenatally tend to have higher stress hormones after birth, according to a new Dartmouth-led study published in Scientific Reports. While previous research has reported examples of maternal stress experience predicting offspring stress hormones in different species, this study is the first to empirically demonstrate the impact of prenatal stress on offspring stress hormone levels using data from all known studies across vertebrates.
Through a meta-analysis of 114 results from a total of 39 observational and experimental studies across 14 vertebrate species, including birds, snakes, sheep and humans, the study examines the impact of prenatal exposure to maternal stress on offspring. The researchers analyzed the role of the hypothalamic pituitary adrenal (HPA)-axis, the stress physiological system that is shared across all vertebrates, which ultimately, results in the production of stress hormones known as “glucocorticoids.” The HPA-axis is the hormonal system responsible for mobilizing an animal’s stress response. Offspring exposed prenatally to maternal stress were found to have more stress hormone levels (glucocorticoids) after birth. This could reflect a biological adaptation with an evolutionary history, as more stress hormones could increase an animal’s chances for survival in a stressful environment.
In the present study, the researchers tested the strength of the effect of prenatal stress on offspring stress hormone levels across a range of characteristics. Remarkably, the effects of prenatal stress on offspring stress hormones were consistent across species, regardless of evolutionary relationships or factors, such as brain or body size. There were also no differences when considering offspring sex, age of the offspring at the time of assessment, or the timing of the stressor exposure prenatally or its severity.
Only two factors influenced the size of the effect. Experimental studies had a stronger effect than observational studies. In addition, studies that measured glucocorticoid recovery showed a greater association with prenatal stress than was observed at baseline or during peak glucocorticoid response.
“Animals, including humans, modify their stress hormones in response to their environment. Your stress response is set like a thermostat– your body can amp up or down stress hormones in response to anticipated environmental conditions,” explains lead author Zaneta Thayer, an assistant professor of anthropology at Dartmouth.
An animal’s stress response tends to be activated by external factors, such as when its see a predator or whether food is availabile. Higher stress hormone levels among offspring may help extend survival but come at a cost and may affect other physiological systems, such as reproduction. In humans, the mere anticipation of stress or just thinking about prior experiences of discrimination or trauma can activate a stress response. Overactive stress hormones can lead to chronic health problems in humans, including anxiety, depression and cardiovascular disease.
One of the studies included in the meta-analysis looked at how maternal stress hormones in pregnant snow hares changed in relation to the abundance of their natural predators, lynxes, over a 10-year cycle. The research team found that in years where there were more lynxes, snow hare offspring had more stress hormones and anti-predator behaviors.
“Our stress response is meant to be adaptive to acute stress, such as being chased by predators. However, humans’ stress response is often triggered by social evaluative threats and is not serving the adaptive purpose that it was designed for,” added Thayer. “This research confirms what other scientists have long speculated that there are trends across species when it comes to linking prenatal stress and offspring hormonal stress responses.”
Prior work co-authored by Thayer has explored early origins of humans’ health disparities and the impacts of maternal stress during pregnancy on offspring’s postnatal stress hormone levels.
###
Thayer is available for comment at: Zaneta.Marie.Thayer@dartmouth.edu.
Meredith A. Wilson at the University of Illinois Urbana-Champaign, Andrew W. Kim at Northwestern University and Adrian V. Jaeggi at Emory University, also served as co-authors of the study.
Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.
https://sciencesources.eurekalert.org/pub_releases/2018-04/dc-sfh041018.php

Here is information about the Adverse Child Experiences Study. The Centers for Disease Control and Prevention provides access to the peer-reviewed publications resulting from The ACE Study. http://acestudy.org/
https://drwilda.com/2012/11/09/study-some-of-the-effects-of-adverse-stress-do-not-go-away/

Science Daily reported in Infantile memory study points to critical periods in early-life learning for brain development:

A new study on infantile memory formation in rats points to the importance of critical periods in early-life learning on functional development of the brain. The research, conducted by scientists at New York University’s Center for Neural Science, reveals the significance of learning experiences over the first two to four years of human life; this is when memories are believed to be quickly forgotten — a phenomenon known as infantile amnesia.
“What our findings tell us is that children’s brains need to get enough and healthy activation even before they enter pre-school,” explains Cristina Alberini, a professor in NYU’s Center for Neural Science, who led the study. “Without this, the neurological system runs the risk of not properly developing learning and memory functions…”
https://www.sciencedaily.com/releases/2016/07/160718111939.htm

Citation:

Infantile memory study points to critical periods in early-life learning for brain development
Date: July 18, 2016
Source: New York University
Summary:
A new study on infantile memory formation in rats points to the importance of critical periods in early-life learning on functional development of the brain. The research reveals the significance of learning experiences over the first two to four years of human life.

Journal Reference:
1. Alessio Travaglia, Reto Bisaz, Eric S Sweet, Robert D Blitzer, Cristina M Alberini. Infantile amnesia reflects a developmental critical period for hippocampal learning. Nature Neuroscience, 2016; DOI: 10.1038/nn.4348

Our goal as a society should be:

A healthy child in a healthy family who attends a healthy school in a healthy neighborhood ©

Resources:

The Effects of Stress on Your Body
http://www.webmd.com/mental-health/effects-of-stress-on-your-body

The Physical Effects of Long-Term Stress
http://psychcentral.com/lib/2007/the-physical-effects-of-long-term-stress/all/1/

Chronic Stress: The Body Connection
http://www.medicinenet.com/script/main/art.asp?articlekey=53737

Understanding Stress Symptoms, Signs, Causes, and Effects
http://www.helpguide.org/mental/stress_signs.htm

Dr. Wilda says this about that ©

Blogs by Dr. Wilda:
COMMENTS FROM AN OLD FART ©
http://drwildaoldfart.wordpress.com/

Dr. Wilda Reviews ©
http://drwildareviews.wordpress.com/

Dr. Wilda ©
https://drwilda.com/

Michigan State University study: Discrimination harms your health and your partner’s health

10 Dec

The Equal Employment Opportunity Commission (EEOC) list the following types of discrimination:

Discrimination by Type
Learn about the various types of discrimination prohibited by the laws enforced by EEOC. We also provide links to the relevant laws, regulations and policy guidance, and also fact sheets, Q&As, best practices, and other information.
• Age
• Disability
• Equal Pay/Compensation
• Genetic Information
• Harassment
• National Origin
• Pregnancy
• Race/Color
• Religion
• Retaliation
• Sex
• Sexual Harassment
https://www.eeoc.gov/laws/types/

The EEOC describes the following types of laws:

Laws & Guidance
Federal Laws prohibit workplace discrimination and are enforced by EEOC. These are passed by Congress and signed by the President.
Regulations implement federal workplace discrimination laws. They are voted on by the Commission after the public has a formal opportunity to provide comments to EEOC. Find our current regulations, read and comment on proposed regulations, and see our regulatory agenda at the link above.
EEOC Subregulatory Guidance expresses official agency policy and explains how the laws and regulations apply to specific workplace situations. EEOC seeks and obtains input from the public in a variety of ways for these documents before they are voted on by the Commission.
Commission Decisions concern a specific charge of discrimination where the Commission votes to express official agency policy to be applied in similar cases by EEOC. They should not be confused with EEOC’s federal sector appellate decisions in federal employee complaints of discrimination.
Memoranda of Understanding (MOUs) explain how two or more agencies will cooperate and interact when their enforcement responsibilities overlap. MOUs involving other federal agencies must be approved by a majority of the Commissioners. EEOC also enters into MOUs with foreign embassies and consulates to enhance cooperation on matters involving employment discrimination.
EEOC Resource Documents assist the public in understanding existing EEOC positions. Since they do not create new policy, they are not voted on by the Commission.
Workplace Laws Not Enforced by the EEOC
Federal laws prohibiting discrimination or regulating workplace issues that are not enforced by the EEOC. https://www.eeoc.gov/laws/index.cfm
Findlaw describes discrimination.
According to Findlaw discrimination is:
Lawful vs. Unlawful Discrimination
Not all types of discrimination will violate federal and/or state laws that prohibit discrimination. Some types of unequal treatment are perfectly legal, and cannot form the basis for a civil rights case alleging discrimination. The examples below illustrate the difference between lawful and unlawful discrimination.
Example 1: Applicant 1, an owner of two dogs, fills out an application to lease an apartment from Landlord. Upon learning that Applicant 1 is a dog owner, Landlord refuses to lease the apartment to her, because he does not want dogs in his building. Here, Landlord has not committed a civil rights violation by discriminating against Applicant 1 based solely on her status as a pet owner. Landlord is free to reject apartment applicants who own pets.
Example 2: Applicant 2, an African American man, fills out an application to lease an apartment from Landlord. Upon learning that Applicant 2 is an African American, Landlord refuses to lease the apartment to him, because he prefers to have Caucasian tenants in his building. Here, Landlord has committed a civil rights violation by discriminating against Applicant 2 based solely on his race. Under federal and state fair housing and anti-discrimination laws, Landlord may not reject apartment applicants because of their race.
Where Can Discrimination Occur?
Federal and state laws prohibit discrimination against members of protected groups (identified above) in a number of settings, including:
• Education
• Employment
• Housing
• Government benefits and services
• Health care services
• Land use / zoning
• Lending and credit
• Public accommodations (Access to buildings and businesses)
• Transportation
• Voting
Anti-Discrimination Laws
Most laws prohibiting discrimination, and many legal definitions of “discriminatory” acts, originated at the federal level through either:
• Federal legislation, like the Civil Rights Act of 1964 and the Americans with Disabilities Act (ADA).
• Other federal acts (supplemented by court decisions) prohibit discrimination in voting rights, housing, extension of credit, public education, and access to public facilities.
OR
• Federal court decisions, like the U.S. Supreme Court case Brown v. Board of Education, which was the impetus for nationwide racial desegregation of public schools. Other Supreme Court cases have shaped the definition of discriminatory acts like sexual harassment, and the legality of anti-discrimination remedies such as affirmative action programs.
Today, most states have anti-discrimination laws of their own which mirror those at the federal level. For example, in the state of Texas, Title 2 Chapter 21 of the Labor Code prohibits employment discrimination. Many of the mandates in this Texas law are based on Title VII of the Civil Rights Act of 1964, the federal law making employment discrimination unlawful…. http://civilrights.findlaw.com/civil-rights-overview/what-is-discrimination.html

A Michigan State University study reported that discrimination harms both the victim and the victim’s partner.

Science Daily reported in Discrimination harms your health and your partner’s health:

Discrimination not only harms the health and well-being of the victim, but the victim’s romantic partner as well, indicates new research led by a Michigan State University scholar.
The work, which analyzed a nationally representative sample of nearly 2,000 couples, is the first study to consider how the discrimination experiences of both people in a relationship are associated with their health. The findings are published in the journal Social Psychological and Personality Science.
“We found that when an individual experiences discrimination, they report worse health and depression. However, that’s not the full story — this stress spills over and affects the health of their partner as well,” said William Chopik, an assistant professor of psychology who conducted the study with current and former MSU students.
The researchers studied the survey data of 1,949 couples ranging in age from 50 to 94. Survey participants reported on incidents of discrimination, as well as on their health, depression and relationship strain and closeness.
Chopik said the study found that it didn’t matter where the discrimination came from (e.g., because of race, age, gender or other factors). “What matters is that they felt that they were unfairly treated. That’s what had the biggest impact on the person’s health.”
And that discrimination had a spillover affect on the person’s spouse or partner. Because people are embedded in relationships, what happens in those relationships affects our health and well-being, Chopik said…. https://www.sciencedaily.com/releases/2017/12/171207154506.htm

Citation:

Discrimination harms your health, and your partner’s, study shows
Date: December 7, 2017
Source: Michigan State University
Summary:
Discrimination not only harms the health and well-being of the victim, but the victim’s romantic partner as well, indicates new research.

Here is the press release from Michigan State University:

Published: Dec. 7, 2017
Discrimination harms your health – and your partner’s
Contact(s): William Chopik , Andy Henion
Discrimination not only harms the health and well-being of the victim, but the victim’s romantic partner as well, indicates new research led by a Michigan State University scholar.
The work, which analyzed a nationally representative sample of nearly 2,000 couples, is the first study to consider how the discrimination experiences of both people in a relationship are associated with their health. The findings are published in the journal Social Psychological and Personality Science.
“We found that when an individual experiences discrimination, they report worse health and depression. However, that’s not the full story – this stress spills over and affects the health of their partner as well,” said William Chopik, an assistant professor of psychology who conducted the study with current and former MSU students.
The researchers studied the survey data of 1,949 couples ranging in age from 50 to 94. Survey participants reported on incidents of discrimination, as well as on their health, depression and relationship strain and closeness.
Chopik said the study found that it didn’t matter where the discrimination came from (e.g., because of race, age, gender or other factors). “What matters is that they felt that they were unfairly treated. That’s what had the biggest impact on the person’s health.”
And that discrimination had a spillover affect on the person’s spouse or partner. Because people are embedded in relationships, what happens in those relationships affects our health and well-being, Chopik said.
“We found that a lot of the harmful effects of discrimination on health occurs because it’s so damaging to our relationships,” he said. “When one partner experiences discrimination, they bring that stress home with them and it strains the relationship. So this stress not only negatively affects their own health, but their partner’s as well.” http://msutoday.msu.edu/news/2017/discrimination-harms-your-health-and-your-partners/

Discrimination harms relationships and produces toxic environments.

The Tanenbaum Center which honors the work of the late Rabbi Marc Tanenbaum has a really good definition of the “Golden Rule” which is stated in an interview with Joyce Dubensky entitled, The Golden Rule Around the World. https://tanenbaum.org/tanenbaum-resources/the-golden-rule/ At the core of all bullying is a failure to recognize another’s humanity and a basic lack of respect for life. At the core of the demand for personal expression and failure to tolerate opinions which are not like one’s own is a self-centeredness which can destroy the very society it claims to want to protect.

Resources:

Examples of discrimination in society today https://www.khanacademy.org/test-prep/mcat/individuals-and-society/discrimination/a/examples-of-discrimination-in-society-today

The impact of prejudice on society http://www.collegian.psu.edu/news/crime_courts/article_a86ea0dc-270a-11e3-ad90-0019bb30f31a.html

The Effects of Racial, Sexual or Religious Discrimination https://lawlex.org/lex-bulletin/the-effects-of-racial-sexual-or-religious-discrimination/8682

Is discrimination wrong? http://www.debate.org/opinions/is-discrimination-wrong

Where information leads to Hope. © Dr. Wilda.com

Dr. Wilda says this about that ©

Blogs by Dr. Wilda:

COMMENTS FROM AN OLD FART©
http://drwildaoldfart.wordpress.com/

Dr. Wilda Reviews ©
http://drwildareviews.wordpress.com/

Dr. Wilda ©
https://drwilda.com/

New York University study: Infantile memory study points to critical periods in early-life learning for brain development

19 Jul

Prolonged stress can have adverse effects on humans. Moi wrote about the Adverse Childhood Experiences Study in Study: Some of the effects of adverse stress do not go away:

Sarah D. Sparks writes in the Education Week article, Research Traces Impacts of Childhood Adversity:

Research from Dr. Shonkoff’s center and from other experts finds that positive stress—the kind that comes from telling a toddler he can’t have a cookie or a teenager that she’s about to take a pop quiz—causes a brief rise in heart rate and stress hormones. A jolt can focus a student’s attention and is generally considered healthy.

Similarly, a child can tolerate stress that is severe but may be relatively short-term—from the death of a loved one, for example—as long as he or she has support….

‘Toxic’ Recipe

By contrast, so-called “toxic stress” is severe, sustained, and not buffered by supportive relationships.

The same brain flexibility, called plasticity, that makes children open to learning in their early years also makes them particularly vulnerable to damage from the toxic stressors that often accompany poverty: high mobility and homelessness; hunger and food instability; parents who are in jail or absent; domestic violence; drug abuse; and other problems, according to Pat Levitt, a developmental neuroscientist at the University of Southern California and the director of the Keck School of Medicine Center on the Developing Child in Los Angeles…. http://www.edweek.org/ew/articles/2012/11/07/11poverty_ep.h32.html?tkn=QLYF5qldyT3U0BI0xqtD5885mihZIxwbX4qZ&cmp=clp-edweek

Here is information about the Adverse Child Experiences Study. The Centers for Disease Control and Prevention provides access to the peer-reviewed publications resulting from The ACE Study. http://acestudy.org/

https://drwilda.com/2012/11/09/study-some-of-the-effects-of-adverse-stress-do-not-go-away/

Science Daily reported in Infantile memory study points to critical periods in early-life learning for brain development:

A new study on infantile memory formation in rats points to the importance of critical periods in early-life learning on functional development of the brain. The research, conducted by scientists at New York University’s Center for Neural Science, reveals the significance of learning experiences over the first two to four years of human life; this is when memories are believed to be quickly forgotten — a phenomenon known as infantile amnesia.

“What our findings tell us is that children’s brains need to get enough and healthy activation even before they enter pre-school,” explains Cristina Alberini, a professor in NYU’s Center for Neural Science, who led the study. “Without this, the neurological system runs the risk of not properly developing learning and memory functions…”

In their study, which appears in the journal Nature Neuroscience, the researchers examined the mechanisms of infantile memory in rats — i.e., memories created 17 days after birth. This is the equivalent of humans under the age of three and when memories of who, what, when, and where — known as episodic memories — are rapidly forgotten. The phenomenon, referred as to “infantile or childhood amnesia,” is in fact the inability of adults to retrieve episodic memories that took place during the first two to four years of life.

In addressing this matter, Alberini and her colleagues compared rats’ infantile memory with that when they reached 24 days old — that is, when they are capable of forming and retaining long-term memories and at an age that roughly corresponds to humans at six to nine years old.

The episodic memory tested in the rodents was the memory of an aversive experience: a mild foot shock received upon entering in a new place. Adult rats, like humans, remember unpleasant or painful experiences that they had in specific places, and then avoid returning to them.

To do so, rodents were placed in a box divided into two compartments: a “safe” compartment and a “shock” compartment. During the experiment, each rat was placed in the safe compartment with its head facing away from the door. After 10 seconds, the door separating the compartments was automatically opened, allowing the rat access to the shock compartment. If the rat entered the shock compartment, it received a mild foot shock.

The first set of results was not surprising. The authors found infantile amnesia for the 17 day-old rats, which showed avoidance of the “shock” compartment right after the experience, but lost this memory very rapidly: a day later these rats quickly returned to this compartment. In contrast, the rats exposed to the shock compartment at 24 days of life learned and retained the memory for a long time and avoided this place — revealing a memory similar to that of adult rats.

However, remarkably, the younger rats, which had apparently forgotten the initial experience, subsequently showed they actually had kept a trace of the memory. When, later in life, these rats were prompted with reminders — i.e., they were presented with recollections of the context and the foot shock — they indicated having a specific memory, which was revealed by their avoidance of the specific context in which they received a shock at day 17 of life. These findings show how early life experience, although not expressed or remembered, can influence adult life behavior.

The findings raised the following question: what is occurring — neurologically — that explains why memories are retained by the younger rats only in a latent form but are stored and expressed long-term by older ones? Or, more specifically, what occurs during development that enhances the ability to form lasting memories?

A critical period is a developmental stage during which the nervous system is especially sensitive to environmental stimuli. If, during this period, the organism does not receive the appropriate stimuli required to develop a given function, it may be difficult or even impossible to develop that function later in life. Well-known examples of critical period-based functions are sensory functions, like vision, and language acquisition.

The study shows that there is a critical period for episodic learning and that during this period the hippocampus learns to become able to efficiently process and store memories long-term…                               https://www.sciencedaily.com/releases/2016/07/160718111939.htm

Citation:

Infantile memory study points to critical periods in early-life learning for brain development

Date:         July 18, 2016

Source:      New York University

Summary:

A new study on infantile memory formation in rats points to the importance of critical periods in early-life learning on functional development of the brain. The research reveals the significance of learning experiences over the first two to four years of human life.

Journal Reference:

  1. Alessio Travaglia, Reto Bisaz, Eric S Sweet, Robert D Blitzer, Cristina M Alberini. Infantile amnesia reflects a developmental critical period for hippocampal learning. Nature Neuroscience, 2016; DOI: 10.1038/nn.4348

Here is the press release from New York University:

Infantile Memory Study Points to Critical Periods in Early-Life Learning for Brain Development

July 18, 2016

A new study on infantile memory formation in rats points to the importance of critical periods in early-life learning on functional development of the brain. The research, conducted by scientists at New York University’s Center for Neural Science, reveals the significance of learning experiences over the first two to four years of human life; this is when memories are believed to be quickly forgotten—a phenomenon known as infantile amnesia.

“What our findings tell us is that children’s brains need to get enough and healthy activation even before they enter pre-school,” explains Cristina Alberini, a professor in NYU’s Center for Neural Science, who led the study. “Without this, the neurological system runs the risk of not properly developing learning and memory functions.”

The other authors of the study, conducted in collaboration with the Icahn School of Medicine at Mt. Sinai, included: Alessio Travaglia, a post-doctoral researcher at NYU; Reto Bisaz, an NYU research scientist at the time of the study; Eric Sweet, a post-doctoral fellow at the Icahn School of Medicine at Mt. Sinai; and Robert Blitzer, a professor at the Icahn School of Medicine at Mt. Sinai.

In their study, which appears in the journal Nature Neuroscience, the researchers examined the mechanisms of infantile memory in rats—i.e., memories created 17 days after birth. This is the equivalent of humans under the age of three and when memories of who, what, when, and where–known as episodic memories–are rapidly forgotten. The phenomenon, referred as to “infantile or childhood amnesia,” is in fact the inability of adults to retrieve episodic memories that took place during the first two to four years of life.

In addressing this matter, Alberini and her colleagues compared rats’ infantile memory with that when they reached 24 days old—that is, when they are capable of forming and retaining long-term memories and at an age that roughly corresponds to humans at six to nine years old.

The episodic memory tested in the rodents was the memory of an aversive experience: a mild foot shock received upon entering in a new place. Adult rats, like humans, remember unpleasant or painful experiences that they had in specific places, and then avoid returning to them.

To do so, rodents were placed in a box divided into two compartments: a “safe” compartment and a “shock” compartment. During the experiment, each rat was placed in the safe compartment with its head facing away from the door. After 10 seconds, the door separating the compartments was automatically opened, allowing the rat access to the shock compartment. If the rat entered the shock compartment, it received a mild foot shock.

The first set of results was not surprising. The authors found infantile amnesia for the 17 day-old rats, which showed avoidance of the “shock” compartment right after the experience, but lost this memory very rapidly: a day later these rats quickly returned to this compartment. In contrast, the rats exposed to the shock compartment at 24 days of life learned and retained the memory for a long time and avoided this place—revealing a memory similar to that of adult rats.

However, remarkably, the younger rats, which had apparently forgotten the initial experience, subsequently showed they actually had kept a trace of the memory. When, later in life, these rats were prompted with reminders—i.e., they were presented with recollections of the context and the foot shock—they indicated having a specific memory, which was revealed by their avoidance of the specific context in which they received a shock at day 17 of life. These findings show how early life experience, although not expressed or remembered, can influence adult life behavior.

The findings raised the following question: what is occurring—neurologically—that explains why memories are retained by the younger rats only in a latent form but are stored and expressed long-term by older ones? Or, more specifically, what occurs during development that enhances the ability to form lasting memories?

To address this, the scientists focused on the brain’s hippocampus, which previous scholarship has shown is necessary for encoding new episodic memories. Here, in a series of experiments similar to the box tests, they found that if the hippocampus was inactive, the ability of younger rats to form latent memories and recall them later by reminders as they got older was diminished. They then found that mechanisms of “critical periods” are fundamental for establishing these infantile memories.

A critical period is a developmental stage during which the nervous system is especially sensitive to environmental stimuli. If, during this period, the organism does not receive the appropriate stimuli required to develop a given function, it may be difficult or even impossible to develop that function later in life. Well-known examples of critical period-based functions are sensory functions, like vision, and language acquisition.

The study shows that there is a critical period for episodic learning and that during this period the hippocampus learns to become able to efficiently process and store memories long-term.

“Early in life, while the brain cannot efficiently form long-term memories, it is ‘learning’ how to do so, making it possible to establish the abilities to memorize long-term,” explains Alberini. “However, the brain needs stimulation through learning so that it can get in the practice of memory formation—without these experiences, the ability of the neurological system to learn will be impaired.”

These studies, the researchers observe, suggest that using learning and environmental interventions during a critical period may significantly help to address learning disabilities.

The research was supported, in part, by grants from the National Institute of Mental Health (R01-MH074736, R01-NS072359), part of the National Institutes of Health, and the Geneva-based Agalma Foundation.

This Press Release is in the following Topics:
Research, Arts and Science, Faculty

Type: Press Release

Press Contact: James Devitt | (212) 998-6808

Our goal as a society should be:

A healthy child in a healthy family who attends a healthy school in a healthy neighborhood ©

Resources:

The Effects of Stress on Your Body                                                                       http://www.webmd.com/mental-health/effects-of-stress-on-your-body

The Physical Effects of Long-Term Stress                                                              http://psychcentral.com/lib/2007/the-physical-effects-of-long-term-stress/all/1/

Chronic Stress: The Body Connection                                                      http://www.medicinenet.com/script/main/art.asp?articlekey=53737

Understanding Stress Symptoms, Signs, Causes, and Effects                     http://www.helpguide.org/mental/stress_signs.htm

Dr. Wilda says this about that ©

Blogs by Dr. Wilda:

COMMENTS FROM AN OLD FART ©                                                http://drwildaoldfart.wordpress.com/

Dr. Wilda Reviews ©                                                                         http://drwildareviews.wordpress.com/

Dr. Wilda ©                                                                                                                https://drwilda.com/

University of North Carolina Chapel Hill study: Stress felt by children shows up in their art

9 Dec

Both the culture and the economy are experiencing turmoil. For some communities, the unsettled environment is a new phenomenon, for other communities, children have been stressed for generations. According to the article, Understanding Depression which was posted at the Kids Health site:

Depression is the most common mental health problem in the United States. Each year it affects 17 million people of all age groups, races, and economic backgrounds.
As many as 1 in every 33 children may have depression; in teens, that number may be as high as 1 in 8. http://kidshealth.org/parent/emotions/feelings/understanding_depression.html

Jyoti Madhusoodanan and Nature magazine reported in the Scientific American article, Stress Alters Children’s Genomes:

Growing up in a stressful social environment leaves lasting marks on young chromosomes, a study of African American boys has revealed. Telomeres, repetitive DNA sequences that protect the ends of chromosomes from fraying over time, are shorter in children from poor and unstable homes than in children from more nurturing families…
http://www.scientificamerican.com/article/stress-alters-childrens-genomes/?WT.mc_id=SA_Facebook

Not only are the child’s gene’s altered, but there are behavioral indications of the stress being felt by the child.

Will Huntsberry of NPR wrote in the article, Kids’ Drawings Speak Volumes About Home:

When children reach 6 years old, their drawings matter.

Not because of those purple unicorns or pinstripe dragons but because of how kids sketch themselves and the very real people in their lives.

In a new study, researchers found that children who experienced chaos at home — including high levels of noise, excessive crowding, clutter and lack of structure — were more likely to draw themselves at a distance from their parents or much smaller in size relative to other figures.

In some cases, these kids drew themselves with drooping arms and indifferent or sad faces.

Their drawings were a reflection of this simple fact: Chaos at home meant parents were interacting with them less and, in many cases, the interactions that were happening were shorter and interrupted.

As a result, kids ended up with a depreciated sense of self, says Roger Mills-Koonce, who led the study with Bharathi Zvara at UNC-Chapel Hill. To be clear, Mills-Koonce did not blame parents or caretakers but called this kind of stress in the home a “function of poverty….”                                                                                                                                http://www.npr.org/blogs/ed/2014/12/08/368693069/kids-drawings-speak-volumes-about-home

Citation:

The Mediating Role of Parenting in the Associations Between Household Chaos and Children’s Representations of Family Dysfunction

Zvara, B. J., Mills-Koonce, W. R., Garrett-Peters, P., Wagner, N. J., Vernon-Feagans, L., Cox, M., & the Family Life Project Key Contributors

2014

From the abstract: “Children’s drawings are thought to reflect their mental representations of self and their interpersonal relations within families. Household chaos is believed to disrupt key proximal processes related to optimal development. The present study examines the mediating role of parenting behaviors in the relations between two measures of household chaos, instability and disorganization, and how they may be evidenced in children’s representations of family dysfunction as derived from their drawings. The sample (N = 962) is from a longitudinal study of rural poverty exploring the ways in which child, family, and contextual factors shape development over time. Findings reveal that, after controlling for numerous factors including child and primary caregiver covariates, there were significant indirect effects from cumulative family disorganization, but not cumulative family instability, on children’s representation of family dysfunction through parenting behaviors. Results suggest that the proximal effects of daily disorganization outweigh the effects of periodic instability overtime.”

Related Project(s):

Children Living in Rural Poverty: The Continuation of the Family Life Project
Family Life Project

Available here: Attachment & Human Development

Or, you may utilize your local academic library to locate this copyrighted material.

Citation: Zvara, B. J., Mills-Koonce, W. R., Garrett-Peters, P., Wagner, N. J., Vernon-Feagans, L., Cox, M., & the Family Life Project Key Contributors. (2014). The mediating role of parenting in the associations between household chaos and children’s representations of family dysfunction. Attachment & Human Development. Advance online publication. doi:10.1080/14616734.2014.966124

DOI: 10.1080/14616734.2014.966124

http://fpg.unc.edu/resources/mediating-role-parenting-associations-between-household-chaos-and-childrens-representation

If you or your child needs help for depression or another illness, then go to a reputable medical provider. There is nothing wrong with taking the steps necessary to get well.

Related:

Schools have to deal with depressed and troubled children

https://drwilda.wordpress.com/2011/11/15/schools-have-to-deal-with-depressed-and-troubled-children/

School psychologists are needed to treat troubled children

https://drwilda.wordpress.com/2012/02/27/school-psychologists-are-needed-to-treat-troubled-children/

Resources:

  1. About.Com’s Depression In Young Children                                                          http://depression.about.com/od/child/Young_Children.htm
  2. Psych Central’s Depression In Young Children                                                      http://depression.about.com/od/child/Young_Children.htm
  3. Psychiatric News’ Study Helps Pinpoint Children With Depression http://psychnews.psychiatryonline.org/newsarticle.aspx?articleid=106034
  4. Family Doctor’s What Is Depression?                                                                               http://familydoctor.org/familydoctor/en/diseases-conditions/depression.html
  5. WebMD’s Depression In Children                                                                                     http://www.webmd.com/depression/guide/depression-children
  6. Healthline’s Is Your Child Depressed?                                                                                   http://www.healthline.com/hlvideo-5min/how-to-help-your-child-through-depression-517095449
  7. Medicine.Net’s Depression In Children http://www.onhealth.com/depression_in_children/article.htm

Where information leads to Hope. © Dr. Wilda.com

Dr. Wilda says this about that ©

Blogs by Dr. Wilda:

COMMENTS FROM AN OLD FART©

http://drwildaoldfart.wordpress.com/

Dr. Wilda Reviews ©

http://drwildareviews.wordpress.com/

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Tulane University Medical School study: Family violence affects the DNA of children

17 Jun

Moi reported about the effect stress has on genes in Penn State study: Stress alters children’s genomes https://drwilda.com/2014/04/08/penn-state-study-stress-alters-childrens-genomes/ A Tulane Medical School study finds that family violence or trauma alters a child’s genomes.

Science Daily reported in the article, Family violence leaves genetic imprint on children:

A new Tulane University School of Medicine study finds that the more fractured families are by domestic violence or trauma, the more likely that children will bear the scars down to their DNA.
Researchers discovered that children in homes affected by domestic violence, suicide or the incarceration of a family member have significantly shorter telomeres, which is a cellular marker of aging, than those in stable households. The findings are published online in the latest issue of the journal Pediatrics.
Telomeres are the caps at the end of chromosomes that keep them from shrinking when cells replicate. Shorter telomeres are linked to higher risks for heart disease, obesity, cognitive decline, diabetes, mental illness and poor health outcomes in adulthood. Researchers took genetic samples from 80 children ages 5 to 15 in New Orleans and interviewed parents about their home environments and exposures to adverse life events….
The study found that gender moderated the impact of family instability. Traumatic family events were more detrimental to young girls as they were more likely to have shortened telomeres. There was also a surprising protective effect for boys: mothers who had achieved a higher level of education had a positive association with telomere length, but only in boys under 10.
Ultimately, the study suggests that the home environment is an important intervention target to reduce the biological impacts of adversity in the lives of young children, Drury said. http://www.sciencedaily.com/releases/2014/06/140617102505.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29&utm_content=FaceBook

Citation:

Family violence leaves genetic imprint on children
Date: June 17, 2014
Source: Tulane University
Summary:
Children in homes affected by violence, suicide, or the incarceration of a family member have significantly shorter telomeres -— a cellular marker of aging — than those in stable households. The study suggests that the home environment is an important intervention target to reduce the biological impacts of adversity in the lives of young children.
Journal Reference:
1. S. S. Drury, E. Mabile, Z. H. Brett, K. Esteves, E. Jones, E. A. Shirtcliff, K. P. Theall. The Association of Telomere Length With Family Violence and Disruption. PEDIATRICS, 2014; 134 (1): e128 DOI: 10.1542/peds.2013-3415

Here is the press release from Tulane University:

Study: Family violence leaves genetic imprint on children
June 16, 2014
Keith Brannon
Phone: 504-862-8789

kbrannon@tulane.edu
A new Tulane University School of Medicine study finds that the more fractured families are by domestic violence or trauma, the more likely that children will bear the scars down to their DNA.
Researchers discovered that children in homes affected by domestic violence, suicide or the incarceration of a family member have significantly shorter telomeres, which is a cellular marker of aging, than those in stable households. The findings are published online in the latest issue of the journal Pediatrics.
Telomeres are the caps at the end of chromosomes that keep them from shrinking when cells replicate. Shorter telomeres are linked to higher risks for heart disease, obesity, cognitive decline, diabetes, mental illness and poor health outcomes in adulthood. Researchers took genetic samples from 80 children ages 5 to 15 in New Orleans and interviewed parents about their home environments and exposures to adverse life events.
“Family-level stressors, such as witnessing a family member get hurt, created an environment that affected the DNA within the cells of the children,” said lead author Dr. Stacy Drury, director of the Behavioral and Neurodevelopmental Genetics Laboratory at Tulane. “The greater the number of exposures these kids had in life, the shorter their telomeres were – and this was after controlling for many other factors, including socioeconomic status, maternal education, parental age and the child’s age.”
The study found that gender moderated the impact of family instability. Traumatic family events were more detrimental to young girls as they were more likely to have shortened telomeres. There was also a surprising protective effect for boys: mothers who had achieved a higher level of education had a positive association with telomere length, but only in boys under 10.
Ultimately, the study suggests that the home environment is an important intervention target to reduce the biological impacts of adversity in the lives of young children, Drury said.

See, School psychologists are needed to treat troubled children https://drwilda.com/2012/02/27/school-psychologists-are-needed-to-treat-troubled-children/

Our goal as a society should be:
A healthy child in a healthy family who attends a healthy school in a healthy neighborhood ©

Related:

Schools have to deal with depressed and troubled children https://drwilda.wordpress.com/2011/11/15/schools-have-to-deal-with-depressed-and-troubled-children/

School psychologists are needed to treat troubled children https://drwilda.wordpress.com/2012/02/27/school-psychologists-are-needed-to-treat-troubled-children/

Battling teen addiction: ‘Recovery high schools’ https://drwilda.wordpress.com/2012/07/08/battling-teen-addiction-recovery-high-schools/

Resources:

About.Com’s Depression In Young Children http://depression.about.com/od/child/Young_Children.htm

Psych Central’s Depression In Young Children http://depression.about.com/od/child/Young_Children.htm

Psychiatric News’ Study Helps Pinpoint Children With Depression
http://psychnews.psychiatryonline.org/newsarticle.aspx?articleid=106034

Family Doctor’s What Is Depression? http://familydoctor.org/familydoctor/en/diseases-conditions/depression.html

WebMD’s Depression In Children http://www.webmd.com/depression/guide/depression-children

Healthline’s Is Your Child Depressed? http://www.healthline.com/hlvideo-5min/how-to-help-your-child-through-depression-517095449

Medicine.Net’s Depression In Children http://www.onhealth.com/depression_in_children/article.htm

If you or your child needs help for depression or another illness, then go to a reputable medical provider. There is nothing wrong with taking the steps necessary to get well.

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