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University of Melbourne and Aalborg University study: How convincing is a Y-chromosome profile match between suspect and crime scene? Study aims to improve the validity and intelligibility of Y-chromosome evidence presented in court

4 Nov

Sarah C. P. Williams wrote in the Science article, Y Chromosome Is More Than a Sex Switch:

The small, stumpy Y chromosome—possessed by male mammals but not females, and often shrugged off as doing little more than determining the sex of a developing fetus—may impact human biology in a big way. Two independent studies have concluded that the sex chromosome, which shrank millions of years ago, retains the handful of genes that it does not by chance, but because they are key to our survival. The findings may also explain differences in disease susceptibility between men and women.
“The old textbook description says that once maleness is determined by a few Y chromosome genes and you have gonads, all other sex differences stem from there,” says geneticist Andrew Clark of Cornell University, who was not involved in either study. “These papers open up the door to a much richer and more complex way to think about the Y chromosome….” http://www.sciencemag.org/news/2014/04/y-chromosome-more-sex-switch

See, National Institute of Standards and Technology study: Courtroom use of ‘Likelihood Ratio’ not consistently supported by scientific reasoning approach https://wordpress.com/posts/drwilda.com and More Innocent People on Death Row Than Estimated: Study http://time.com/79572/more-innocent-people-on-death-row-than-estimated-study/

Science Daily reported in How convincing is a Y-chromosome profile match between suspect and crime scene?

David Balding of the University of Melbourne, Australia and Mikkel Andersen of Aalborg University in Denmark have developed new, open-source software that can help understand how many people in a population will match a single Y-chromosome profile detected at a crime scene, which they describe in a new study in PLOS Genetics.
Forensic analysis of Y-chromosome DNA is especially useful when a small amount of male DNA is mixed in with a large amount of female DNA, such as occurs in sexual assault cases. Explaining this evidence in court, however, is difficult because the Y chromosome passes down mostly unchanged from fathers to sons, so a single Y-chromosome profile can be shared by dozens of men in a population.
Instead of a match probability or database count, Balding and Andersen propose that courts be told about the likely number of matching males in the population, and the possible consequences of their relatedness, which is often more distant than uncle or cousin but much closer than for a random man. They also show how the distribution of matching males can be affected by database information, and suggest ways to present this information in court to make clear that Y-chromosome evidence cannot definitively identify the culprit, but can dramatically reduce the number of possible sources of the DNA. The court must then decide if it has enough other evidence to identify the suspect as the source of the Y-chromosome profile, rather than one of his matching (distant) relatives.
After the introduction of DNA profiling using non-sex chromosomes, the procedure had problems that, once addressed, made profiling a powerful tool that has revolutionized forensic science. Now, Y chromosome profiling must undergo the same process to quantify the results in a way that is valid and directly interpretable to courts. The new software presented in this study could be used to improve the accuracy of Y chromosome evidence and to increase its understanding by judges and jurors…. https://www.sciencedaily.com/releases/2017/11/171103142725.htm

Citation:

How convincing is a Y-chromosome profile match between suspect and crime scene?
Study aims to improve the validity and intelligibility of Y-chromosome evidence presented in court
Date: November 3, 2017
Source: PLOS
Summary:
Scientists have developed new, open-source software that can help understand how many people in a population will match a single Y-chromosome profile detected at a crime scene.
Journal Reference:
1. Mikkel M. Andersen, David J. Balding. How convincing is a matching Y-chromosome profile? PLOS Genetics, 2017; 13 (11): e1007028 DOI: 10.1371/journal.pgen.1007028

Here is the press release:

Public Release: 3-Nov-2017
How convincing is a Y-chromosome profile match between suspect and crime scene?
Study aims to improve the validity and intelligibility of Y-chromosome evidence presented in court
PLOS
David Balding of the University of Melbourne, Australia and Mikkel Andersen of Aalborg University in Denmark have developed new, open-source software that can help understand how many people in a population will match a single Y-chromosome profile detected at a crime scene, which they describe in a new study in PLOS Genetics.
Forensic analysis of Y-chromosome DNA is especially useful when a small amount of male DNA is mixed in with a large amount of female DNA, such as occurs in sexual assault cases. Explaining this evidence in court, however, is difficult because the Y chromosome passes down mostly unchanged from fathers to sons, so a single Y-chromosome profile can be shared by dozens of men in a population.
Instead of a match probability or database count, Balding and Andersen propose that courts be told about the likely number of matching males in the population, and the possible consequences of their relatedness, which is often more distant than uncle or cousin but much closer than for a random man. They also show how the distribution of matching males can be affected by database information, and suggest ways to present this information in court to make clear that Y-chromosome evidence cannot definitively identify the culprit, but can dramatically reduce the number of possible sources of the DNA. The court must then decide if it has enough other evidence to identify the suspect as the source of the Y-chromosome profile, rather than one of his matching (distant) relatives.
After the introduction of DNA profiling using non-sex chromosomes, the procedure had problems that, once addressed, made profiling a powerful tool that has revolutionized forensic science. Now, Y chromosome profiling must undergo the same process to quantify the results in a way that is valid and directly interpretable to courts. The new software presented in this study could be used to improve the accuracy of Y chromosome evidence and to increase its understanding by judges and jurors.
David Balding adds: “We think this work is going to make a big improvement to how Y profile evidence is presented in courts. We will soon extend this work to mixtures of Y-chromosome profiles from multiple males, and also address the corresponding problem for the maternally-inherited mtDNA profiles. Our approach also allows us to include information from any relatives of the suspect whose profile is already available, and we will be working to develop that aspect.”
###
In your coverage please use this URL to provide access to the freely available article in PLOS Genetics:
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007028
Citation: Andersen MM, Balding DJ (2017) How convincing is a matching Y-chromosome profile? PLoS Genet 13(11): e1007028. https://doi.org/10.1371/journal.pgen.1007028
Image Credit: Mikkel Andersen
Image Caption: A simplified illustration of a simulated population of males, with lines indicating father-son links. The suspected source of the DNA, whose profile matches that from the crime scene, is shown in red and other males with matching Y profiles, who are often close relatives, are yellow. The dashed line separates the last three generations, those further back in time will typically be already dead or otherwise unlikely to be of interest (depending on the circumstances of the crime).
Funding: The authors wish to thank the Isaac Newton Institute for Mathematical Sciences, Cambridge UK, for support and hospitality during the programme Probability and Statistics in Forensic Science, where this paper was conceived. The programme was supported by EPSRC grant no EP/K032208/1. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing Interests: The authors have declared that no competing interests exist.
Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system. https://www.eurekalert.org/pub_releases/2017-11/p-hci103117.php

Mathew Shaer wrote in the The False Promise of DNA Testing: The forensic technique is becoming ever more common—and ever less reliable.:

Modern forensic science is in the midst of a great reckoning. Since a series of high-profile legal challenges in the 1990s increased scrutiny of forensic evidence, a range of long-standing crime-lab methods have been deflated or outright debunked. Bite-mark analysis—a kind of dental fingerprinting that dates back to the Salem witch trials—is now widely considered unreliable; the “uniqueness and reproducibility” of ballistics testing has been called into question by the National Research Council. In 2004, the FBI was forced to issue an apology after it incorrectly connected an Oregon attorney named Brandon Mayfield to that spring’s train bombings in Madrid, on the basis of a “100 percent” match to partial fingerprints found on plastic bags containing detonator devices. Last year, the bureau admitted that it had reviewed testimony by its microscopic-hair-comparison analysts and found errors in at least 90 percent of the cases. A thorough investigation is now under way…. https://www.theatlantic.com/magazine/archive/2016/06/a-reasonable-doubt/480747/

The reliability of the evidence and the ability of a particular accused to defend against evidence presented in a court hearing is crucial to preventing the innocent from being convicted.

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City University of New York study: More underrepresented students obtain science degrees and pursue STEM, due to research mentoring

11 Sep

Many educators have long recognized that the impact of social class affects both education achievement and life chances after completion of education. There are two impacts from diversity, one is to broaden the life experience of the privileged and to raise the expectations of the disadvantaged. Social class matters in not only other societies, but this one as well.
A few years back, the New York Times did a series about social class in America. That series is still relevant. Janny Scott and David Leonhardt’s overview, Shadowy Lines That Still Divide describes the challenges faced by schools trying to overcome the disparity in education. The complete series can be found at Social Class http://www.nytimes.com/2005/05/15/national/class/OVERVIEW-FINAL.html?pagewanted=all&_r=0 and http://www.nytimes.com/2005/05/15/national/class/OVERVIEW-FINAL.html   Jason DeParle reported in the New York Times article, For Poor Strivers, Leap to College Often Ends in a Hard Fall http://www.nytimes.com/2012/12/23/education/poor-students-struggle-as-class-plays-a-greater-role-in-success.html?hpw&_r=0

Social class and background may not only affect an individual student’s choice of major, but their completion of college in that major. Nick De Santis reported in the Chronicle of Higher Education article, Report Examines College Students’ Attrition From STEM Majors:

Twenty-eight percent of bachelor’s-degree students who began their postsecondary education in the 2003-4 academic year chose a major in science, technology, engineering, or mathematics at some point within six years, but 48 percent of students who entered those fields during that period had left them by the spring of 2009, according to a report released on Tuesday by the National Center for Education Statistics, the U.S. Education Department’s statistical arm.
The report, which addresses attrition from the so-called STEM fields, also includes information on students pursuing associate degrees. It says that 20 percent of such students had chosen a STEM major within that six-year period and notes that 69 percent of them had left the STEM fields by the spring of 2009.
Of the students who left STEM fields, the report says, roughly half switched their major to a non-STEM field, and the rest left college without earning a degree or certificate. The report notes that fields such as the humanities and education experienced higher levels of attrition than did the STEM disciplines.
The report identifies several factors associated with a higher probability of switching out of STEM majors, such as taking lighter STEM course loads or less-challenging math classes in the first year, and earning lower grades in STEM courses than in others….
http://chronicle.com/blogs/ticker/report-examines-college-students-attrition-from-stem-majors/69705?cid=pm&utm_source=pm&utm_medium=en

A Cornell University study found that should women remain in STEM programs they might be preferred for tenure-track faculty positions.  http://www.usnews.com/news/stem-solutions/articles/2015/04/13/report-faculty-prefer-women-for-tenure-track-stem-positions

Science Daily reported in More underrepresented students obtain science degrees and pursue STEM, due to research mentoring:

Graduation rates among science majors at a large minority-serving college have nearly tripled since the implementation of an undergraduate research experience (URE) program ten years ago. A new study in the Journal of Research in Science Teaching indicates that undergraduates who participate in mentored research not only graduate more often with science degrees, but also attend graduate school and pursue STEM careers at higher rates.

Established in 2006, John Jay College’s Program for Research Initiatives in Science and Math (PRISM) is an URE program that enables undergraduates to carry out guided scientific research. Although undergraduate STEM research has been de rigueur at major research universities, public Minority- and Hispanic-serving institutions like John Jay have historically struggled to provide their students with equivalent experiences and to keep them competitive with their majority peers. Tailored to students and faculty, PRISM has benefited both participants and the college. An extensive case study revealed that graduation rates from science have nearly tripled since PRISM’s inception, that the number of students pursuing graduate degrees has grown nearly ten fold, and that students receive author credit on journal articles more often than at other institutions. Furthermore, John Jay has seen a growth in both external funding and in full-time faculty focused on STEM research…                                                                                     https://www.sciencedaily.com/releases/2016/09/160908120344.htm

Citation:

More underrepresented students obtain science degrees and pursue STEM, due to research mentoring

Date:          September 8, 2016

Source:      The City University of New York

Summary:

A new study indicates that undergraduates who participate in mentored research not only graduate more often with science degrees, but also attend graduate school and pursue STEM careers at higher rates.

Journal Reference:

  1. Anthony Carpi, Darcy M. Ronan, Heather M. Falconer, Nathan H. Lents. Cultivating minority scientists: Undergraduate research increases self-efficacy and career ambitions for underrepresented students in STEM. Journal of Research in Science Teaching, 2016; DOI: 10.1002/tea.21341

Here is the press release from City University of New York:

Public Release: 8-Sep-2016

More underrepresented students obtain science degrees & pursue STEM, due to research mentoring

The City University of New York

New York, NY – Graduation rates among science majors at a large minority-serving college have nearly tripled since the implementation of an undergraduate research experience (URE) program ten years ago. A new study in the Journal of Research in Science Teaching indicates that undergraduates who participate in mentored research not only graduate more often with science degrees, but also attend graduate school and pursue STEM careers at higher rates.

Established in 2006, John Jay College’s Program for Research Initiatives in Science and Math (PRISM) is an URE program that enables undergraduates to carry out guided scientific research. Although undergraduate STEM research has been de rigueur at major research universities, public Minority- and Hispanic-serving institutions like John Jay have historically struggled to provide their students with equivalent experiences and to keep them competitive with their majority peers. Tailored to students and faculty, PRISM has benefited both participants and the college. An extensive case study revealed that graduation rates from science have nearly tripled since PRISM’s inception, that the number of students pursuing graduate degrees has grown nearly ten fold, and that students receive author credit on journal articles more often than at other institutions. Furthermore, John Jay has seen a growth in both external funding and in full-time faculty focused on STEM research.

To reach these conclusions, researchers made use of institutional and program data collected over three years, interviews and focus groups, and surveys. Notably, the study found that PRISM positively affected students’ decisions to pursue graduate degrees and STEM careers, impacting Black and Hispanic participants more significantly than their White and Asian counterparts. Lead author Anthony Carpi, Professor of Environmental Toxicology and Dean of Research at John Jay College, City University of New York, said, “We were delighted to see the impact that undergraduate research experiences have on our students’ career plans. John Jay has a robust and diverse pipeline of students moving on to post-graduate professional careers in STEM fields, and it is exciting to see these students becoming skilled scientists.”

Norman Lederman, Distinguished Professor of Mathematics and Science at the Illinois Institute of Technology, said, “It has long been known that actual research experiences in science and mathematics impact students’ attitudes toward science and mathematics as well as the STEM career aspirations of pre-college and college students. It has also been known that under represented students tend to select themselves out of STEM fields for a variety of social and cultural reasons. The PRISM program at John Jay College has produced extremely compelling results and it serves as an impressive model for other universities, especially those that do not initially have high-level research profiles.”

This study represents the initial stage of a multi-pronged evaluation of John Jay’s URE program with subsequent phases focusing on quantitative comparisons. For now, PRISM appears not only to redress some of the education and employment inequities faced by minority students, but also to serve as an example to other institutions that wish to send more underrepresented students into the STEM workforce.

###

The City University of New York is the nation’s leading urban public university. Founded in New York City in 1847, the University comprises 24 institutions: 11 senior colleges, seven community colleges, and other professional schools. The University serves nearly 275,000 degree-credit students and 218,083 adult, continuing and professional education students.

For more information, please contact Shante Brooker.

The Cornell study points to the need for good science education to prepare a diverse population for opportunities. K-12 education must not only prepare students by teaching basic skills, but they must prepare students for training after high school, either college or vocational. There should not only be a solid education foundation established in K-12, but there must be more accurate evaluation of whether individual students are “college ready.”

Related:

Girls and math phobia
https://drwilda.com/2012/01/20/girls-and-math-phobia/

Study: Gender behavior differences lead to higher grades for girls

https://drwilda.com/2013/01/07/study-gender-behavior-differences-lead-to-higher-grades-for-girls/

University of Missouri study: Counting ability predicts future math ability of preschoolers https://drwilda.com/2012/11/15/university-of-missouri-study-counting-ability-predicts-future-math-ability-of-preschoolers/

Is an individualized program more effective in math learning?
https://drwilda.com/2012/10/10/is-an-individualized-program-more-effective-in-math-learning

Where information leads to Hope. © Dr. Wilda.com

Dr. Wilda says this about that ©

Blogs by Dr. Wilda:

COMMENTS FROM AN OLD FART©
http://drwildaoldfart.wordpress.com/

Dr. Wilda Reviews ©
http://drwildareviews.wordpress.com/

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American Academy of Pediatrics opposes drug testing in schools

5 Apr

Substance abuse is often a manifestation of other problems that child has either at home or poor social relations including low self esteem. Dr. Alan Leshner summarizes the reasons children use drugs in why do Sally and Johnny use drugs? http://archives.drugabuse.gov/Published_Articles/Sally.html The National Council on Alcohol and Drug Dependence lists Signs and Symptoms:

1. Physical and health warning signs of drug abuse
• Eyes that are bloodshot or pupils that are smaller or larger than normal.
• Frequent nosebleeds–could be related to snorted drugs (meth or cocaine).
• Changes in appetite or sleep patterns. Sudden weight loss or weight gain.
• Seizures without a history of epilepsy.
• Deterioration in personal grooming or physical appearance.
• Injuries/accidents and person won’t or can’t tell you how they got hurt.
• Unusual smells on breath, body, or clothing.
• Shakes, tremors, incoherent or slurred speech, impaired or unstable coordination.

2. Behavioral signs of drug abuse
• Drop in attendance and performance at work or school; loss of interest in extracurricular activities, hobbies, sports or exercise; decreased motivation.
• Complaints from co-workers, supervisors, teachers or classmates.
• Unusual or unexplained need for money or financial problems; borrowing or stealing; missing money or valuables.
• Silent, withdrawn, engaging in secretive or suspicious behaviors.
• Sudden change in relationships, friends, favorite hangouts, and hobbies.
• Frequently getting into trouble (arguments, fights, accidents, illegal activities).

3. Psychological warning signs of drug abuse
• Unexplained change in personality or attitude.
• Sudden mood changes, irritability, angry outbursts or laughing at nothing.
• Periods of unusual hyperactivity or agitation.
• Lack of motivation; inability to focus, appearing lethargic or “spaced out.”
• Appearing fearful, withdrawn, anxious, or paranoid, with no apparent reason.
Signs and symptoms of Drug Dependence:
Drug dependence involves all the symptoms of drug abuse, but also involves another element: physical dependence.
1. Tolerance: Tolerance means that, over time, you need more drugs to feel the same effects. Do they use more drugs now than they used before? Do they use more drugs than other people without showing obvious signs of intoxication?
2. Withdrawal: As the effect of the drugs wear off, the person may experience withdrawal symptoms: anxiety or jumpiness; shakiness or trembling; sweating, nausea and vomiting; insomnia; depression; irritability; fatigue or loss of appetite and headaches. Do they use drugs to steady the nerves, stop the shakes in the morning? Drug use to relieve or avoid withdrawal symptoms is a sign of addiction.
In severe cases, withdrawal from drugs can be life-threatening and involve hallucinations, confusion, seizures, fever, and agitation. These symptoms can be dangerous and should be managed by a physician specifically trained and experienced in dealing with addiction.
3. Loss of Control: Using more drugs than they wanted to, for longer than they intended, or despite telling themselves that they wouldn’t do it this time.
4. Desire to Stop, But Can’t: They have a persistent desire to cut down or stop their drug use, but all efforts to stop and stay stopped, have been unsuccessful.
5. Neglecting Other Activities: They are spending less time on activities that used to be important to them (hanging out with family and friends, exercising or going to the gym, pursuing hobbies or other interests) because of the use of drugs.
6. Drugs Take Up Greater Time, Energy and Focus: They spend a lot of time using drugs, thinking about it, or recovering from its effects. They have few, if any, interests, social or community involvements that don’t revolve around the use of drugs.
7. Continued Use Despite Negative Consequences: They continue to use drugs even though they know it’s causing problems. As an example, person may realize that their drug use is interfering with ability to do their job, is damaging their marriage, making problems worse, or causing health problems, but they continue to use…. https://ncadd.org/learn-about-drugs/signs-and-symptoms

Remember, these are very general signs, specific drugs, narcotics, and other substances may have different signs, it is important to know the specific signs.

Kathryn Doyle of Reuters wrote in Experts caution against random drug testing in schools:

Schools should not be using random drug tests to catch or deter drug abusers, the American Academy of Pediatrics advises in an updated policy statement.

The Academy recommends against school-based “suspicionless” drug testing in the new issue of the journal Pediatrics.

Identifying kids who use drugs and entering them into treatment programs should be a top priority, but there is little evidence that random drug testing helps accomplish this, said Dr. Sharon Levy, director of the adolescent substance abuse program at Boston Children’s Hospital and lead author of the new policy statement…

Scientifically, the best way to test the value of random drug tests would be to put some kids into a drug testing program and others not, in a single school, but practically, that is difficult to accomplish. Instead, researchers have compared schools with drug testing programs to similar schools without them – and found mixed results.

One study did find a short-term reduction in kids’ self-reported drug use at a school with random testing, but the kids were followed for a relatively short period and reductions in use applied only to the drugs included in the testing. This is a problem since most drug testing panels do not include alcohol, Levy said.
“It’s possible that you do get some prevention out of these programs, but on the other hand it seems very expensive, very invasive, and has pretty limited results,” she said.

Adolescent drug use is usually sporadic, so even a kid who does use illegal substances may easily pass a random annual test and then feel comfortable to use freely for the rest of the year, she said.

Drug tests can result in false positives, and even a true positive says nothing about frequency or quantity of drug use, according to Ken C. Winters of the psychiatry department at the University of Minnesota Medical School in Minneapolis, who is not in the AAP.
http://newsdaily.com/2015/03/experts-caution-against-random-drug-testing-in-schools/#eI8U6EOrbeuGbOZZ.99

Citation:

• From the American Academy of Pediatrics
Adolescent Drug Testing Policies in Schools
1. Sharon Levy, MD, MPH, FAAP,
2. Miriam Schizer, MD, MPH, FAAP,
3. COMMITTEE ON SUBSTANCE ABUSE
Abstract
More than a decade after the US Supreme Court established the legality of school-based drug testing, these programs remain controversial, and the evidence evaluating efficacy and risks is inconclusive. The objective of this technical report is to review the relevant literature that explores the benefits, risks, and costs of these programs.

Here is the AAP statement:

AAP Opposes In School Drug Testing Due to Lack of Evidence
3/30/2015
Drug testing can be useful for pediatricians and other health care providers to assess substance use or mental health disorders in adolescents, but random drug testing in schools is a controversial approach not recommended by the American Academy of Pediatrics (AAP).

In an updated policy statement and technical report, “Adolescent Drug Testing Policies in Schools,” in the April 2015 Pediatrics (published online March 30), the AAP encourages and supports the efforts of schools to identify and address student substance abuse, but recommends against the use of school-based drug testing programs, often called suspicionless or random drug testing.

Proponents of random drug testing refer to potential advantages such as students avoiding drug use because of the negative consequences associated with having a positive drug test results, while opponents of random drug testing agree that the disadvantages are much greater, and can include deterioration in the student-school relationship, confidentiality of students’ medical records, and mistakes in interpreting drug tests that can result in false-positive results.

The AAP recommends against the use of school-based drug testing programs because of limited evidence of efficacy and potential risks associated with this procedure. Pediatricians support the development of effective substance abuse services in schools, along with appropriate referral policies in place for adolescents struggling with substance abuse disorders.
# # #

The American Academy of Pediatrics is an organization of 62,000 primary care pediatricians, pediatric medical subspecialists and pediatric surgical specialists dedicated to the health, safety and well-being of infants, children, adolescents and young adults.
https://www.aap.org/en-us/about-the-aap/aap-press-room/Pages/AAP-Opposes-In-school-Drug-Testing-Due-to-Lack-of-Evidence.aspx

The National Institute on Drug Abuse (Institute) has some great information about drug testing. In Frequently Asked Questions About Drug Testing in Schools, the Institute discusses drug testing.

Why test teenagers at all?

Teens are especially vulnerable to drug abuse, when the brain and body are still developing. Most teens do not use drugs, but for those who do, it can lead to a wide range of adverse effects on the brain, the body, behavior and health.
Short term: Even a single use of an intoxicating drug can affect a person’s judgment and decisonmaking—resulting in accidents, poor performance in a school or sports activity, unplanned risky behavior, and the risk of overdosing.
Long term: Repeated drug abuse can lead to serious problems, such as poor academic outcomes, mood changes (depending on the drug: depression, anxiety, paranoia, psychosis), and social or family problems caused or worsened by drugs.
Repeated drug use can also lead to the disease of addiction. Studies show that the earlier a teen begins using drugs, the more likely he or she will develop a substance abuse problem or addiction. Conversely, if teens stay away from drugs while in high school, they are less likely to develop a substance abuse problem later in life….
Is random drug testing of students legal?
In June 2002, the U.S. Supreme Court broadened the authority of public schools to test students for illegal drugs. Voting 5 to 4 in Pottawatomie County v. Earls, the court ruled to allow random drug tests for all middle and high school students participating in competitive extracurricular activities. The ruling greatly expanded the scope of school drug testing, which previously had been allowed only for student athletes.
Just because the U.S. Supreme Court said student drug testing for adolescents in competitive extracurricular activities is constitutional, does that mean it is legal in my city or state?
A school or school district that is interested in adopting a student drug testing program should seek legal expertise so that it complies with all federal, state, and local laws. Individual state constitutions may dictate different legal thresholds for allowing student drug testing. Communities interested in starting student drug testing programs should become familiar with the law in their respective states to ensure proper compliance. http://www.drugabuse.gov/related-topics/drug-testing/faq-drug-testing-in-schools

The primary issue is whether students have privacy rights.

Your Debate.com summarizes the pros and cons of School Drug Testing:

PRO 1
The main purpose of random school drug testing is not to catch kids using drugs, it to keep them from ever using them. Once their using drugs its harder for them to break their addiction. With many employers drug testing its very important for a kid’s future not to use drugs. Drug use is responsible for many crimes. Its worth the inconvenience for all our future.
CON 2
One of the fundamental features of our legal system is that we are presumed innocent of any wrongdoing unless and until the government proves otherwise. Random drug testing of student athletes turns this presumption on its head, telling students that we assume they are using drugs until they prove to the contrary with a urine sample.
CON 3
“If school officials have reason to believe that a particular student is using drugs, they already have the power to require that student to submit to a drug test,” said ACLU-NJ Staff Attorney David Rocah.
CON 4
The constitutional prohibition against “unreasonable” searches also embodies the principle that merely belonging to a certain group is not a sufficient reason for a search, even if many members of that group are suspected of illegal activity. Thus, for example, even if it were true that most men with long hair were drug users, the police would not be free to stop all long haired men and search them for drugs.
PRO 5
Peer pressure is the greatest cause of kids trying drugs. If by testing the athletes or other school leaders, we can get them to say no to drugs, it will be easier for other kids to say no.
CON 6
Some also argue that students who aren’t doing anything wrong have nothing to fear. This ignores the fact that what they fear is not getting caught, but the loss of dignity and trust that the drug test represents. And we should all be afraid of government officials who believe that a righteous cause warrants setting aside bedrock constitutional protections. The lesson that our schools should be teaching is respect for the Constitution and for students’ dignity and privacy, not a willingness to treat cherished constitutional principles as mere platitudes. http://www.youdebate.com/DEBATES/school_drug_testing.HTM

See, What Are the Benefits of Drug Testing?http://www.livestrong.com/article/179407-what-are-the-benefits-of-drug-testing/

Substance abuse is often a manifestation of other problems that child has either at home or poor social relations including low self-esteem.

Resources:

Adolescent Substance Abuse Knowledge Base

http://www.crchealth.com/troubled-teenagers/teenage-substance-abuse/adolescent-substance-abuse/signs-drug-use/

Warning Signs of Teen Drug Abuse

http://parentingteens.about.com/cs/drugsofabuse/a/driug_abuse20.htm?r=et

Al-Anon and Alateen

http://al-anon.alateen.org/

National Clearinghouse for Drug and Alcohol Information

http://www.samhsa.gov/

The U.S. Department of Health and Human Services has a very good booklet for families What is Substance Abuse Treatment?

http://www.samhsa.gov/kap

The National Institute on Drug Abuse (NIDA) has a web site for teens and parents that teaches about drug abuse NIDA for Teens: The Science Behind Drug Abuse

http://teens.drugabuse.gov/

Where information leads to Hope. © Dr. Wilda.com

Dr. Wilda says this about that ©

Blogs by Dr. Wilda:

COMMENTS FROM AN OLD FART©
http://drwildaoldfart.wordpress.com/

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http://drwildareviews.wordpress.com/

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University of Illinois and Princeton University study: Stereotypes that women are not as brilliant as men result in gender inequity in academia

15 Jan

Many girls and women who have the math and science aptitude for a science career don’t enter scientific fields. Cheryl B. Schrader wrote in the St Louis Post-Dispatch article, STEM education: Where the girls are not:

Compounding this issue, the gender gap in these fields is widening…
While the majority of U.S. college students today are female, they remain a minority in many science and engineering fields. If universities are to meet the future demands of our economy, we can’t leave half of the college-bound population on the sidelines.
How can we change that? The STEMconnector report offers some hints.
Female high school students who are interested in these fields often gravitate toward biology, chemistry, marine biology and science — areas often associated with a desire to make the world a better place. Women tend to be drawn to these service-oriented professions….http://www.stltoday.com/news/opinion/columns/stem-education-where-the-girls-are-not/article_ae33c7b7-6a7b-5011-8d2a-138bc1538357.html

See, STEM Connector http://store.stemconnector.org/Where-Are-the-STEM-Students_p_9.html

Stephanie Castillo reported in the Medical Daily article, Gender Inequality In Academia Stems From Assumption Women Aren’t As Brilliant As Men:

A new study published in the journal Science continues to support the idea gender inequality exists in academia.

According to researchers from the University of Illinois and Princeton University, women are underrepresented in academic fields, such as the sciences, the humanities, social sciences, and math, because of stereotypes. Namely, the idea is that women’s intellectual abilities are inferior to those of men. Cue the eye rolling.

The study surveyed more than 1,800 graduate students, post-doctoral researchers and faculty members across 30 academic disciplines, asking them the qualities required for success in their fields. When it came to the STEM fields (science, technology, engineering, and math), as well as the humanities and social sciences, women were underrepresented because of the premium practitioners put on brilliance.

“We’re not saying brilliance — or valuing brilliance — is a bad thing. And we’re not saying women are not brilliant or that being brilliant isn’t helpful to one’s academic career. Our data don’t address that,” Andrei Cimpian, lead study author and psychology professor at Illinois, explained in a press release. “What they suggest is that conveying to your students a belief that brilliance is required for success may have a differential effect on males and females that are looking to pursue careers in your field.”

Cimpian’s explanation held up after he and his team tested for three additional hypotheses regarding female underrepresentation: one, women avoid working long hours; two, it’s harder for women to break into these highly selective fields; and three, men simply outnumber women “in fields that require analytical, systematical reasoning.” Neither of these was able to predict women’s representation in academia as well as brilliance.

But, just because Cimpian’s study didn’t address the idea “women aren’t brilliant” or “being brilliant isn’t helpful” doesn’t mean it’s not a thing. Because if it were true no one is saying or making these assumptions, there would be more women in academia. Cimpian himself said there’s no convincing evidence men and women differ intellectually in ways that would be relevant to their success working in science — it’s mainly the perceived or presumed differences between women and men.

The idea women are “inferior” to men started somewhere, so where should we be looking in order to come up with the solution? One study published in the journal Life Science Education suggested the classroom…http://www.medicaldaily.com/gender-inequality-academia-stems-assumption-women-arent-brilliant-men-317984

Citation:

Science 16 January 2015:
Vol. 347 no. 6219 pp. 262-265
DOI: 10.1126/science.1261375

  • Report

Expectations of brilliance underlie gender distributions across academic disciplines

  1. Sarah-Jane Leslie1,*,,
  2. Andrei Cimpian2,*,,
  3. Meredith Meyer3,
  4. Edward Freeland4

+ Author Affiliations

  1. 1Department of Philosophy, Princeton University, Princeton, NJ 08544, USA.
  2. 2Department of Psychology, University of Illinois at Urbana-Champaign, Champaign, IL 61820, USA.
  3. 3Department of Psychology, Otterbein University, Westerville, OH 43081, USA.
  4. 4Survey Research Center, Princeton University, Princeton, NJ 08544, USA.
  1. *These authors contributed equally to the work.

The gender imbalance in STEM subjects dominates current debates about women’s underrepresentation in academia. However, women are well represented at the Ph.D. level in some sciences and poorly represented in some humanities (e.g., in 2011, 54% of U.S. Ph.D.’s in molecular biology were women versus only 31% in philosophy). We hypothesize that, across the academic spectrum, women are underrepresented in fields whose practitioners believe that raw, innate talent is the main requirement for success, because women are stereotyped as not possessing such talent. This hypothesis extends to African Americans’ underrepresentation as well, as this group is subject to similar stereotypes. Results from a nationwide survey of academics support our hypothesis (termed the field-specific ability beliefs hypothesis) over three competing hypotheses.

  • Received for publication 17 September 2014.
  • Accepted for publication 25 November 2014.

Related Web Sites

Read the Full Text

The editors suggest the following Related Resources on Science sites

In Science Magazine

  • Perspective Social Science Gender inequality in science
    • Andrew M. Penner

Science 16 January 2015: 234-235.

http://www.sciencemag.org/content/347/6219/262.short

Here is the press release from the University of Illinois:

Public Release: 15-Jan-2015 Study supports new explanation of gender gaps in academia

University of Illinois at Urbana-Champaign

CHAMPAIGN, Ill. — It isn’t that women don’t want to work long hours or can’t compete in highly selective fields, and it isn’t that they are less analytical than men, researchers report in a study of gender gaps in academia. It appears instead that women are underrepresented in academic fields whose practitioners put a lot of emphasis on the importance of being brilliant – a quality many people assume women lack.

The new findings are reported in the journal Science.

The research, led by University of Illinois psychology professor Andrei Cimpian and Princeton University philosophy professor Sarah-Jane Leslie , focused on a broad swath of academic disciplines, including those in the sciences, the humanities, social sciences and math.

The researchers focused on the culture of different fields, reasoning that stereotypes of women’s inferior intellectual abilities might help explain why women are underrepresented in fields – such as physics or philosophy – that idolize geniuses.

The team surveyed more than 1,800 graduate students, post-doctoral researchers and faculty members in 30 academic disciplines and, among other things, asked them what qualities were required for success in their fields. Across the board, in the sciences, technology, engineering and math (the so-called STEM fields), as well as in the humanities and social sciences, women were found to be underrepresented in those disciplines whose practitioners put a premium on brilliance.

“We’re not saying brilliance – or valuing brilliance – is a bad thing,” Cimpian said. “And we’re not saying women are not brilliant or that being brilliant isn’t helpful to one’s academic career. Our data don’t address that. What they suggest is that conveying to your students a belief that brilliance is required for success may have a differential effect on males and females that are looking to pursue careers in your field.”

The team also tested three other hypotheses that might help explain women’s underrepresentation in some fields: one, that women avoid careers that require them to work long hours; two, that women are less able than men to get into highly selective fields; and three, that women are outnumbered by men in fields that require analytical, systematical reasoning.

“We found that none of these three alternative hypotheses was able to predict women’s representation across the academic spectrum,” Leslie said. “A strong emphasis on brilliance among practitioners of particular fields was the best predictor of women’s underrepresentation in those fields.”

The researchers are still investigating whether women are actively avoiding fields that focus on cultivating brilliant individuals, or if practitioners in those fields are discriminating against women based on their beliefs about women’s aptitudes. A combination of the two is certainly plausible, Cimpian said.

“There is no convincing evidence in the literature that men and women differ intellectually in ways that would be relevant to their success across the entire range of fields we surveyed,” Cimpian said. “So it is most likely that female underrepresentation is not the result of actual differences in intellectual ability – but rather the result of perceived or presumed differences between women and men.”

###

Editor’s notes:

To reach Andrei Cimpian, call 217-333-0852; email acimpian@illinois.edu.

The paper, “Expectations of brilliance underlie gender distributions across academic disciplines” is available to members of the media from scipak@aaas.org.

How classes are taught and how girls and woman are encouraged makes a huge difference in the fields women choose for their education and work.

Phoebe Parke of CNN wrote in the article, Ask the experts: How do we get girls into STEM?

  1. “The toys and games that young girls play with mold their educational and career interests; they create dreams of future careers.” says Andrea Guendelman, co-founder of Developher

  2. “Introduce girls early to role models of other women In STEM” suggests Regina Agyare, founder of Soronko Solutions….

  3. “It’s important to engage girls in STEM at an early age and keep them interested.” adds Patty L. Fagin, PhD, Head of School at Stuart Country Day School of the Sacred Heart.

  4. “There’s no magic recipe for getting girls into STEM, but we know early and positive exposure makes an impact.” Karen Horting, CEO and Executive Director at the Society of Women Engineers told CNN….

  5. “Start them young.” is Michelle Sun, Founder and CEO of First Code Academy‘s advice….

  6. “I believe one on one mentoring programs with accomplished female STEM professionals will help bring girls in to the STEM field.” says Adeola Shasanya who recently co-founded Afro-Tech Girls and works at the Lagos State Electricity Board as an Electrical Engineering and Renewables Consultant….

  7. Haiyan Zhang, Innovation Director at Lift London, Microsoft Studios believes confidence is key; “Insatiable curiosity and the self confidence to make change in the world — two qualities that are key to instil in the female innovators of the future….

  8. “Women are the future of technology and today’s technology is fun and cool.” says Weili Dai, President and Co-founder of Marvell Technology Group

  9. “Time and again, I hear from women who chose their STEM career because they were inspired by a successful woman who proved it could be done.” adds Suw Charman-Anderson, Founder of Ada Lovelace Day….

  10. “To get more girls in STEM let’s go for collective action…” says Julie Kantor, Chief Partnership Officer at Million Women Mentors

http://www.cnn.com/2014/10/27/world/europe/how-to-get-girls/

It is going to take a variety of strategies which include mentoring, exposure to what is now considered nontraditional fields and encouragement of girls and women not only entering nontraditional fields, but staying the course.

Related:

Study: Gender behavior differences lead to higher grades for girls

https://drwilda.com/2013/01/07/study-gender-behavior-differences-lead-to-higher-grades-for-girls/

Girls and math phobia

https://drwilda.com/2012/01/20/girls-and-math-phobia/

University of Missouri study: Counting ability predicts future math ability of preschoolers

https://drwilda.com/2012/11/15/university-of-missouri-study-counting-ability-predicts-future-math-ability-of-preschoolers/

Is an individualized program more effective in math learning?

https://drwilda.com/2012/10/10/is-an-individualized-program-more-effective-in-math-learning/

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University of California San Francisco study: Dozens of genes associated with autism

29 Oct

The number of children with autism appears to be growing. The Centers for Disease Control and Prevention provides statistics on the number of children with autism in the section Data and Statistics:

Prevalence

  • It is estimated that between 1 in 80 and 1 in 240 with an average of 1 in 110 children in the United States have an ASD. [Read article]

  • ASDs are reported to occur in all racial, ethnic, and socioeconomic groups, yet are on average 4 to 5 times more likely to occur in boys than in girls.  However, we need more information on some less studied populations and regions around the world. [Read article]

  • Studies in Asia, Europe, and North America have identified individuals with an ASD with an approximate prevalence of 0.6% to over 1%. A recent study in South Korea reported a prevalence of 2.6%. [Data table ]

  • Approximately 13% of children have a developmental disability, ranging from mild disabilities such as speech and language impairments to serious developmental disabilities, such as intellectual disabilities, cerebral palsy, and autism.  [Read article] http://www.cdc.gov/ncbddd/autism/data.html

In order for children with autism to reach their full potential there must be early diagnosis and treatment.

Science Daily reported in Dozens of genes associated with autism in new research:

Two major genetic studies of autism, led in part by UC San Francisco scientists and involving more than 50 laboratories worldwide, have newly implicated dozens of genes in the disorder. The research shows that rare mutations in these genes affect communication networks in the brain and compromise fundamental biological mechanisms that govern whether, when, and how genes are activated overall.

The two new studies, published in the advance online edition of Nature on October 29, 2014, tied mutations in more than 100 genes to autism. Sixty of these genes met a “high-confidence” threshold indicating that there is a greater than 90 percent chance that mutations in those genes contribute to autism risk.

The majority of the mutations identified in the new studies are de novo (Latin for “afresh”) mutations, meaning they are not present in unaffected parents’ genomes but arise spontaneously in a single sperm or egg cell just prior to conception of a child.

The genes implicated in the new studies fall into three broad classes: they are involved in the formation and function of synapses, which are sites of nerve-cell communication in the brain; they regulate, via a process called transcription, how the instructions in other genes are relayed to the protein-making machinery in cells; and they affect how DNA is wound up and packed into cells in a structure known as chromatin. Because modifications of chromatin structure are known to lead to changes in how genes are expressed, mutations that alter chromatin, like those that affect transcription, would be expected to affect the activity of many genes.

One of the new Nature studies made use of data from the Simons Simplex Collection (SSC), a permanent repository of DNA samples from nearly 3,000 families created by the Simons Foundation Autism Research Initiative. Each SSC family has one child affected with autism, parents unaffected by the disorder and, in a large proportion, unaffected siblings. The second study was conducted under the auspices of the Autism Sequencing Consortium (ASC), an initiative supported by the National Institute of Mental Health that allows scientists from around the world to collaborate on large genomic studies that couldn’t be done by individual labs.

“Before these studies, only 11 autism genes had been identified with high confidence, and we have now more than quadrupled that number,” said Stephan Sanders, PhD, assistant professor of psychiatry at UCSF, co-first author on the SSC study, and co-author on the ASC study. Based on recent trends, Sanders estimates that gene discovery will continue at a quickening pace, with as many as 1,000 genes ultimately associated with autism risk.

“There has been a lot of concern that 1,000 genes means 1,000 different treatments, but I think the news is much brighter than that,” said Matthew W. State, MD, PhD, chair and Oberndorf Family Distinguished Professor in Psychiatry at UCSF. State was co-leader of the Nature study focusing on the SSC and a senior participant in the study organized by the ASC, of which he is a co-founder. ”There is already strong evidence that these mutations converge on a much smaller number key biological functions. We now need to focus on these points of convergence to begin to develop novel treatments….”                                                                                                                            http://www.sciencedaily.com/releases/2014/10/141029141223.htm

Citation:

Dozens of genes associated with autism in new research

Date:             October 29, 2014

Source:         University of California, San Francisco (UCSF)

Summary:

Two major genetic studies of autism, involving more than 50 laboratories worldwide, have newly implicated dozens of genes in the disorder. The research shows that rare mutations in these genes affect communication networks in the brain and compromise fundamental biological mechanisms that govern whether, when, and how genes are activated overall.

Nature | Article

Synaptic, transcriptional and chromatin genes disrupted in autism

Nature

(2014)

doi:10.1038/nature13772

Received

18 May 2014

Accepted

18 August 2014

Published online

29 October 2014

Abstract

  • Abstract•

The genetic architecture of autism spectrum disorder involves the interplay of common and rare variants and their impact on hundreds of genes. Using exome sequencing, here we show that analysis of rare coding variation in 3,871 autism cases and 9,937 ancestry-matched or parental controls implicates 22 autosomal genes at a false discovery rate (FDR) < 0.05, plus a set of 107 autosomal genes strongly enriched for those likely to affect risk (FDR < 0.30). These 107 genes, which show unusual evolutionary constraint against mutations, incur de novo loss-of-function mutations in over 5% of autistic subjects. Many of the genes implicated encode proteins for synaptic formation, transcriptional regulation and chromatin-remodelling pathways. These include voltage-gated ion channels regulating the propagation of action potentials, pacemaking and excitability–transcription coupling, as well as histone-modifying enzymes and chromatin remodellers—most prominently those that mediate post-translational lysine methylation/demethylation modifications of histones.                                                                                   http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13772.html

Here is the press release from the University of California San Francisco:

Dozens of Genes Associated with Autism in New Research

Functions of Newly Identified Genes Converge on a Few Important Biological Processes

By Pete Farley on October 29, 2014 | Email | Print

Two major genetic studies of autism, led in part by UC San Francisco scientists and involving more than 50 laboratories worldwide, have newly implicated dozens of genes in the disorder. The research shows that rare mutations in these genes affect communication networks in the brain and compromise fundamental biological mechanisms that govern whether, when, and how genes are activated overall.

The two new studies, published in the advance online edition of Nature on October 29, 2014, tied mutations in more than 100 genes to autism. Sixty of these genes met a “high-confidence” threshold indicating that there is a greater than 90 percent chance that mutations in those genes contribute to autism risk.

The majority of the mutations identified in the new studies are de novo (Latin for “afresh”) mutations, meaning they are not present in unaffected parents’ genomes but arise spontaneously in a single sperm or egg cell just prior to conception of a child.

The genes implicated in the new studies fall into three broad classes: they are involved in the formation and function of synapses, which are sites of nerve-cell communication in the brain; they regulate, via a process called transcription, how the instructions in other genes are relayed to the protein-making machinery in cells; and they affect how DNA is wound up and packed into cells in a structure known as chromatin. Because modifications of chromatin structure are known to lead to changes in how genes are expressed, mutations that alter chromatin, like those that affect transcription, would be expected to affect the activity of many genes.

One of the new Nature studies made use of data from the Simons Simplex Collection (SSC), a permanent repository of DNA samples from nearly 3,000 families created by the Simons Foundation Autism Research Initiative. Each SSC family has one child affected with autism, parents unaffected by the disorder and, in a large proportion, unaffected siblings. The second study was conducted under the auspices of the Autism Sequencing Consortium (ASC), an initiative supported by the National Institute of Mental Health that allows scientists from around the world to collaborate on large genomic studies that couldn’t be done by individual labs.

“Before these studies, only 11 autism genes had been identified with high confidence, and we have now more than quadrupled that number,” said Stephan Sanders, PhD, assistant professor of psychiatry at UCSF, co-first author on the SSC study, and co-author on the ASC study. Based on recent trends, Sanders estimates that gene discovery will continue at a quickening pace, with as many as 1,000 genes ultimately associated with autism risk.

“There has been a lot of concern that 1,000 genes means 1,000 different treatments, but I think the news is much brighter than that,” said Matthew W. State, MD, PhD, chair and Oberndorf Family Distinguished Professor in Psychiatry at UCSF. State was co-leader of the Nature study focusing on the SSC and a senior participant in the study organized by the ASC, of which he is a co-founder. ”There is already strong evidence that these mutations converge on a much smaller number key biological functions. We now need to focus on these points of convergence to begin to develop novel treatments.

Autism, which is marked by deficits in social interaction and language development, as well as by repetitive behaviors and restricted interests, is known to have a strong genetic component. But until a few years ago, genomic research had failed to decisively associate individual genes with the disorder.

The two new studies highlight the factors that have radically changed that picture, State said. One is the advent of next-generation sequencing (NGS), which allows researchers to read each of the “letters” in the DNA code at unprecedented speed. Another is the establishment of the SSC; a 2007 study had suggested that de novo mutations would play a significant role in autism risk, and the SSC was specifically designed to help test that idea by allowing for close comparisons between children with autism and their unaffected parents and siblings. Lastly, collaborative initiatives such as the ASC are enabling teams of researchers around the world to work closely together, pooling their resources to create large datasets with sufficient statistical power to draw valid conclusions.

The large research teams behind each of the two new studies used a form of NGS known as “whole-exome” sequencing, a letter-by-letter analysis of just the portion of the genome that encodes proteins.

In November 2013, a study led by A. Jeremy Willsey, a graduate student in State’s lab, showed that the functional roles of the nine high-confidence autism risk genes that had then been discovered all converged on a single cell type in a particular place in the brain at a particular time during fetal development. Willsey is a co-author on both of the new Nature studies, which State believes will further accelerate our understanding of how the myriad of genes involved in autism affect basic biological pathways in the brain.

“These genes carry really large effects,” State said. “That we now have a bounty of dozens of genes, and a clear path forward to find perhaps hundreds more, provides an incredible foundation for understanding the biology of autism and finding new treatments.”

UCSF is the nation’s leading university exclusively focused on health. Now celebrating the 150th anniversary of its founding as a medical college, UCSF is dedicated to transforming health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It includes top-ranked graduate schools of dentistry, medicine, nursing and pharmacy; a graduate division with world-renowned programs in the biological sciences, a preeminent biomedical research enterprise and top-tier hospitals, UCSF Medical Center and UCSF Benioff Children’s Hospitals.

It is imperative that ALL women receive prenatal care particularly poor and those women at risk of difficult pregnancies. Early diagnosis of autism gives the child the best chance of achieving their potential.

Related:

Autism and children of color                                                                                                                                                                                       https://drwilda.com/tag/children-of-color-with-autism/

Archives of Pediatrics and Adolescent Medicine study: Kids with autism more likely to be bullied                                     https://drwilda.com/2012/09/06/archives-of-pediatrics-and-adolescent-medicine-study-kids-with-autism-more-likely-to-be-bullied/

Father’s age may be linked to Autism and Schizophrenia                                                                                                     https://drwilda.com/2012/08/26/fathers-age-may-be-linked-to-autism-and-schizophrenia/

Chelation treatment for autism might be harmful                                                                                                                                                  https://drwilda.com/2012/12/02/chelation-treatment-for-autism-might-be-harmful/

Journal of American Medical Association study: Folic acid may reduce autism risk                                               https://drwilda.com/tag/folic-acid-in-pregnancy-may-lower-autism-risk/

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University of Illinois Urbana- Champaign study: ADHD kids may benefit with FITKids exercise intervention

21 Oct

Moi wrote in ADHD coaching to improve a child’s education outcome:
The American Academy of Child and Adolescent Psychiatry discusses the primary symptoms of ADHD in the article, What Is ADHD:

The primary symptoms of ADHD are hyperactivity, impulsivity, and inattention.
Hyperactive children always seem to be in motion. A child who is hyperactive may move around touching or playing with whatever is around, or talk continually. During story time or school lessons, the child might squirm around, fidget, or get up and move around the room. Some children wiggle their feet or tap their fingers. A teenager or adult who is hyperactive may feel restless and need to stay busy all the time.
Impulsive children often blurt out comments without thinking first. They may often display their emotions without restraint. They may also fail to consider the consequences of their actions. Such children may find it hard to wait in line or take turns. Impulsive teenagers and adults tend to make choices that have a small immediate payoff rather than working toward larger delayed rewards….

ADHD News has a synopsis of the ADHD news     http://www.medicalnewstoday.com/categories/adhd

https://drwilda.com/2012/03/31/adhd-coaching-to-improve-a-childs-education-outcome/

Julia Lawrence of Education News reported about a Quebec study in the article, Study: ADHD Drugs Don’t Improve Academic Performance in Kids:

Shirley S. Wang of The Wall Street Journal writes about one such study published in June which looked at academic outcomes of Quebec students prescribed ADHD drugs like Ritalin and Adderall over a span of 11 years. Researchers concluded that boys who were taking drugs academically underperformed peers with the same symptoms who were not medicated. The working paper published by the National Bureau of Economic Research also reported that girls who took ADHD drugs had higher incidence of emotional problems than ones who did not.

“The possibility that [medication] won’t help them [in school] needs to be acknowledged and needs to be closely monitored,” says economics professor Janet Currie, an author on the paper and director of the Center for Health & Wellbeing, a health policy institute at Princeton University. Kids may not get the right dose to see sustained benefits, or they may stop taking the medication because side effects or other drawbacks outweigh the benefits, she says.

Why drugs that claim to improve concentration, focus and emotional control don’t lead to academic improvement is a question that has puzzled researchers for some time — and answering the question could be the key to effective ADHD treatment in children. Finding an effective treatment regime could help a lot of kids; according to Centers for Disease Control and Prevention, there are 2.7 million children currently on ADHD drugs of some kind in the United States alone.

http://www.educationnews.org/parenting/study-adhd-drugs-dont-improve-academic-performance-in-kids/#sthash.HkASci3N.dpuf

This study is in accord with research from Yale University.

Geneva Pittman of Reuters wrote in the article, Be cautious of mind-altering drugs for kids: doctors:

Focusing on stimulants typically used to treat attention deficit hyperactivity disorder, or ADHD, researchers said the number of diagnoses and prescriptions have risen dramatically over the past two decades.

Young people with the disorder clearly benefit from treatment, lead author Dr. William Graf emphasized, but the medicines are increasingly being used by healthy youth who believe they will enhance their concentration and performance in school.

According to the National Institute on Drug Abuse, 1.7 percent of eighth graders and 7.6 percent of 12th graders have used Adderall, a stimulant, for nonmedical reasons.
Some of those misused medicines are bought on the street or from peers with prescriptions; others may be obtained legally from doctors.

“What we’re saying is that because of the volume of drugs and the incredible increase… the possibility of overdiagnosis and overtreatment is clearly there,” said Graf, from Yale University in New Haven, Connecticut.

In their statement, published in the journal Neurology, he and his colleagues say doctors should not give prescriptions to teens who ask for medication to enhance concentration against their parents’ advice. http://www.reuters.com/article/2013/03/13/us-medications-kids-idUSBRE92C17H20130313

A University of Illinois study indicates that exercise might be an effective therapy.

James Hamlin wrote in the Atlantic article: Exercise Is ADHD Medication:

Physical movement improves mental focus, memory, and cognitive flexibility; new research shows just how critical it is to academic performance.

Mental exercises to build (or rebuild) attention span have shown promise recently as adjuncts or alternatives to amphetamines in addressing symptoms common to Attention Deficit Hyperactivity Disorder (ADHD). Building cognitive control, to be better able to focus on just one thing, or single-task, might involve regular practice with a specialized video game that reinforces “top-down” cognitive modulation, as was the case in a popular paper in Nature last year. Cool but still notional. More insipid but also more clearly critical to addressing what’s being called the ADHD epidemic is plain old physical activity.

This morning the medical journal Pediatrics published research that found kids who took part in a regular physical activity program showed important enhancement of cognitive performance and brain function. The findings, according to University of Illinois professor Charles Hillman and colleagues, “demonstrate a causal effect of a physical program on executive control, and provide support for physical activity for improving childhood cognition and brain health.” If it seems odd that this is something that still needs support, that’s because it is odd, yes. Physical activity is clearly a high, high-yield investment for all kids, but especially those attentive or hyperactive. This brand of research is still published and written about as though it were a novel finding, in part because exercise programs for kids remain underfunded and underprioritized in many school curricula, even though exercise is clearly integral to maximizing the utility of time spent in class…..                                                                                                                       http://www.theatlantic.com/health/archive/2014/09/exercise-seems-to-be-beneficial-to-children/380844/?single_page=true

Citation:

Effects of the FITKids Randomized Controlled Trial on Executive Control and Brain Function

  1. Charles H. Hillman, PhDa,
  2. Matthew B. Pontifex, PhDb,
  3. Darla M. Castelli, PhDc,
  4. Naiman A. Khan, PhD, RDa,
  5. Lauren B. Raine, BSa,
  6. Mark R. Scudder, BSa,
  7. Eric S. Drollette, BSa,
  8. Robert D. Moore, MSa,
  9. Chien-Ting Wu, PhDd, and
  10. Keita Kamijo, PhDe

+ Author Affiliations

1.     aDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois; 2.     bDepartment of Kinesiology, Michigan State University, East Lansing, Michigan; 3.     cDepartment of Kinesiology and Health Education, University of Texas at Austin, Austin, Texas; 4.     dDepartment of Exercise Science, Schreiner College, Kerrville, Texas; and 5.     eSchool of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan

Abstract

OBJECTIVE: To assess the effect of a physical activity (PA) intervention on brain and behavioral indices of executive control in preadolescent children.

METHODS: Two hundred twenty-one children (7–9 years) were randomly assigned to a 9-month afterschool PA program or a wait-list control. In addition to changes in fitness (maximal oxygen consumption), electrical activity in the brain (P3-ERP) and behavioral measures (accuracy, reaction time) of executive control were collected by using tasks that modulated attentional inhibition and cognitive flexibility.

RESULTS: Fitness improved more among intervention participants from pretest to posttest compared with the wait-list control (1.3 mL/kg per minute, 95% confidence interval [CI]: 0.3 to 2.4; d = 0.34 for group difference in pre-to-post change score). Intervention participants exhibited greater improvements from pretest to posttest in inhibition (3.2%, 95% CI: 0.0 to 6.5; d = 0.27) and cognitive flexibility (4.8%, 95% CI: 1.1 to 8.4; d = 0.35 for group difference in pre-to-post change score) compared with control. Only the intervention group increased attentional resources from pretest to posttest during tasks requiring increased inhibition (1.4 µV, 95% CI: 0.3 to 2.6; d = 0.34) and cognitive flexibility (1.5 µV, 95% CI: 0.6 to 2.5; d = 0.43). Finally, improvements in brain function on the inhibition task (r = 0.22) and performance on the flexibility task correlated with intervention attendance (r = 0.24).

CONCLUSIONS: The intervention enhanced cognitive performance and brain function during tasks requiring greater executive control. These findings demonstrate a causal effect of a PA program on executive control, and provide support for PA for improving childhood cognition and brain health.

Key Words:

  • Accepted July 25, 2014.

After-school exercise program enhances cognition in 7-, 8- and 9-year-olds

Date:         September 29, 2014

Source:           University of Illinois at Urbana-Champaign

Summary:

A nine-month-long, randomized controlled trial involving 221 prepubescent children found that those who engaged in moderate-to-vigorous physical activity for at least 60 minutes a day after school saw substantial improvements in their ability to pay attention, avoid distraction and switch between cognitive tasks, researchers report.

Here is the press report from the University of Illinois Urbana- Champaign:

After-school exercise program enhances cognition in 7-, 8- and 9-year-olds

Email Share

9/29/2014 | Diana Yates, Life Sciences Editor | 217-333-5802; diya@illinois.edu

CHAMPAIGN, Ill. — A nine-month-long, randomized controlled trial involving 221 prepubescent children found that those who engaged in moderate-to-vigorous physical activity for at least 60 minutes a day after school saw substantial improvements in their ability to pay attention, avoid distraction and switch between cognitive tasks, researchers report in the journal Pediatrics.

Fitness, cognitive function and brain function improved in children in the FITKids exercise intervention group, researchers report. | Photo by L. Brian Stauffer

Half of the study subjects were randomly assigned to the after-school program and the rest were placed on a wait list. All participants underwent cognitive testing and brain imaging before and after the intervention.

“Those in the exercise group received a structured intervention that was designed for the way kids like to move,” said University of Illinois kinesiology and community health professor Charles Hillman, who led the study. “They performed short bouts of exercise interspersed with rest over a two-hour period.”

The intervention, called FITKids, was based on the CATCH exercise program, a research-based health promotion initiative that was initially funded by the National Institutes of Health and now is used by schools and health departments across the U.S.

The children in the FITKids exercise group wore heart-rate monitors and pedometers during the intervention.

“On average, kids’ heart rates corresponded with a moderate-to-vigorous level of exercise intensity, and they averaged about 4,500 steps during the two-hour intervention,” Hillman said. The children were active about 70 minutes per day.

As expected, fitness increased most in the intervention group over the course of the study.

“We saw about a six percent increase in fitness in children in the FITKids intervention group,” Hillman said. Fitness improved less than one percent in the wait-list control group, he said.

Children in the exercise group also demonstrated substantial increases in “attentional inhibition,” a measure of their ability to block out distractions and focus on the task at hand. And they improved in “cognitive flexibility,” which involves switching between intellectual tasks while maintaining speed and accuracy. Children in the wait-list control group saw minimal improvements in these measures, in line with what would be expected as a result of normal maturation over the nine months, Hillman said.

“Kids in the intervention group improved two-fold compared to the wait-list kids in terms of their accuracy on cognitive tasks,” he said. “And we found widespread changes in brain function, which relate to the allocation of attention during cognitive tasks and cognitive processing speed. These changes were significantly greater than those exhibited by the wait-list kids.

“Interestingly, the improvements observed in the FITKids intervention were correlated with their attendance rate, such that greater attendance was related to greater change in brain function and cognitive performance,” Hillman said.

The study did not distinguish improvements that were the result of increased fitness from those that might stem from the social interactions, stimulation and engagement the children in the intervention group experienced, Hillman said.

“Other research at Georgia Regents University led by Catherine Davis has actually used social and game-playing as their control group, and showed that the cognitive effects of their physical activity intervention are above-and-beyond those that are gained just through social interactions,” he said.

The FITKids program is designed to get children socially engaged in exercise, which is part of what makes it an effective intervention, Hillman said.

“The fact is that kids are social beings; they perform physical activity in a social environment,” he said. “A big reason why kids participate in a structured sports environment is because they find it fun and they make new friends. And this intervention was designed to meet those needs as well.”

The Eunice Kennedy Shriver National Institute of Child Health and Human Development at the National Institutes of Health funded this research.

Editor’s note: To reach Charles Hillman, call 217-244-2663; email chhillma@illinois.edu.

The paper, “Effects of the FITKids Randomized Controlled Trial on Executive Control and Brain Function,” is available online or from the U. of I. News Bureau.

Physically fit children are not only healthier, but are better able to perform better in school. Our goal as a society should be:

A healthy child in a healthy family who attends a healthy school in a healthy neighborhood ©

Reference Links:

Edge Foundation ADHD Coaching Study Executive Summary

http://edgefoundation.org/wp-content/uploads/2011/01/Edge-Foundation-ADHD-Coaching-Research-Report.pdf

Edge Foundation ADHD Coaching Study Full Report

http://edgefoundation.org/wp-content/uploads/2011/01/Edge-Foundation-ADHD-Coaching-Research-Report.pdf

ADHD and College Success: A free guide

http://www.edgefoundation.org/howedgehelps/add-2.html

ADHD and ExecutiveFunctioning

http://edgefoundation.org/blog/2010/10/08/the-role-of-adhd-and-your-brains-executive-functions/

Executive Function, ADHD and Academic Outcomes

http://www.helpforld.com/efacoutcomes.pdf

Louisiana study: Fit children score higher on standardized tests

https://drwilda.com/2012/05/08/louisiana-study-fit-children-score-higher-on-standardized-tests/

If you suspect that your child might have ADHD, you should seek an evaluation from a competent professional who has knowledge of this specialized area of medical practice.

Related:

Studies: ADHD drugs don’t necessarily improve academic performance

https://drwilda.com/2013/07/14/studies-adhd-drugs-dont-necessarily-improve-academic-performance/

ADHD coaching to improve a child’s education outcome

https://drwilda.com/2012/03/31/adhd-coaching-to-improve-a-childs-education-outcome/

An ADHD related disorder: ‘Sluggish Cognitive Tempo’

https://drwilda.com/2014/04/12/an-adhd-related-disorder-sluggish-cognitive-tempo/

Where information leads to Hope. © Dr. Wilda.com

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Blogs by Dr. Wilda:

COMMENTS FROM AN OLD FART©

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Dr. Wilda Reviews ©

http://drwildareviews.wordpress.com/

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King’s College London study: Education achievement reflects many genetically influenced traits

13 Oct

Talking about the influence of genetics and learning is a touchy subject. The 1994 Bell Curve by Herrnstein and Murray started a wild fire. http://www.princeton.edu/~achaney/tmve/wiki100k/docs/The_Bell_Curve.html The King’s College focused on:

The high heritability of exam grades reflects many genetically influenced traits such as personality, behavior problems, and self-efficacy and not just intelligence. http://www.sciencedaily.com/releases/2014/10/141006152151.htm

The study deals with the effect of genetics on emotional intelligence which is very important to achievement.

Jeanne Segal, Ph.D., and Melinda Smith, M.A. wrote the excellent article, Emotional Intelligence (EQ) for HELPGUIDE.Org.

What is emotional intelligence?
Emotional intelligence (EQ) is the ability to identify, use, understand, and manage emotions in positive ways to relieve stress, communicate effectively, empathize with others, overcome challenges, and diffuse conflict. Emotional intelligence impacts many different aspects of your daily life, such as the way you behave and the way you interact with others…. http://www.helpguide.org/mental/eq5_raising_emotional_intelligence.htm

Education achievement requires not only intelligence, but motivation, resilience, and conflict resolution.

Science Daily reported in the article, Why is educational achievement heritable?

New research, led by King’s College London finds that the high heritability of exam grades reflects many genetically influenced traits such as personality, behaviour problems, and self-efficacy and not just intelligence.

The study, published in the Proceedings of the National Academy of Sciences (PNAS), looked at 13,306 twins at age 16 who were part of the Medical Research Council (MRC) funded UK Twins Early Development Study (TEDS). The twins were assessed on a range of cognitive and non-cognitive measures, and the researchers had access to their GCSE (General Certificate of Secondary Education) scores.

In total, 83 scales were condensed into nine domains: intelligence, self-efficacy (confidence in one’s own academic ability), personality, well-being, home environment, school environment, health, parent-reported behaviour problems and child reported behaviour problems.

Identical twins share 100% of their genes, and non-identical twins (just as any other siblings) share 50% of the genes that vary between people. Twin pairs share the same environment (family, schools, teachers etc). By comparing identical and non-identical twins, the researchers were able to estimate the relative contributions of genetic and environmental factors. So, if overall, identical twins are more similar on a particular trait than non-identical twins, the differences between the two groups are due to genetics, rather than environment.

Eva Krapohl, joint first author of the study, from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s, says: “Previous work has already established that educational achievement is heritable. In this study, we wanted to find out why that is. What our study shows is that the heritability of educational achievement is much more than just intelligence — it is the combination of many traits which are all heritable to different extents.

“It is important to point out that heritability does not mean that anything is set in stone. It simply means that children differ in how easy and enjoyable they find learning and that much of these differences are influenced by genetics.”

The researchers found that the heritability of GCSE scores was 62%. Individual traits were between 35% and 58% heritable, with intelligence being the most highly heritable. Together, the nine domains accounted for 75% of the heritability of GCSE scores.

Heritability is a population statistic which does not provide any information at an individual level. It describes the extent to which differences between children can be ascribed to DNA differences, on average, in a particular population at a particular time…. http://www.sciencedaily.com/releases/2014/10/141006152151.htm

Citation:

Why is educational achievement heritable?
Date: October 6, 2014

Source: King’s College London
Summary:
The high heritability of exam grades reflects many genetically influenced traits such as personality, behavior problems, and self-efficacy and not just intelligence. The study looked at 13,306 twins at age 16 . The twins were assessed on a range of cognitive and non-cognitive measures, and the researchers had access to their GCSE (General Certificate of Secondary Education) scores.
The high heritability of educational achievement reflects many genetically influenced traits, not just intelligence
1. Eva Krapohla,1,
2. Kaili Rimfelda,1,
3. Nicholas G. Shakeshafta,
4. Maciej Trzaskowskia,
5. Andrew McMillana,
6. Jean-Baptiste Pingaulta,b,
7. Kathryn Asburyc,
8. Nicole Harlaard,
9. Yulia Kovasa,e,f,
10. Philip S. Daleg, and
11. Robert Plomina,2
Significance
Differences among children in educational achievement are highly heritable from the early school years until the end of compulsory education at age 16, when UK students are assessed nationwide with standard achievement tests [General Certificate of Secondary Education (GCSE)]. Genetic research has shown that intelligence makes a major contribution to the heritability of educational achievement. However, we show that other broad domains of behavior such as personality and psychopathology also account for genetic influence on GCSE scores beyond that predicted by intelligence. Together with intelligence, these domains account for 75% of the heritability of GCSE scores. These results underline the importance of genetics in educational achievement and its correlates. The results also support the trend in education toward personalized learning.
Abstract
Because educational achievement at the end of compulsory schooling represents a major tipping point in life, understanding its causes and correlates is important for individual children, their families, and society. Here we identify the general ingredients of educational achievement using a multivariate design that goes beyond intelligence to consider a wide range of predictors, such as self-efficacy, personality, and behavior problems, to assess their independent and joint contributions to educational achievement. We use a genetically sensitive design to address the question of why educational achievement is so highly heritable. We focus on the results of a United Kingdom-wide examination, the General Certificate of Secondary Education (GCSE), which is administered at the end of compulsory education at age 16. GCSE scores were obtained for 13,306 twins at age 16, whom we also assessed contemporaneously on 83 scales that were condensed to nine broad psychological domains, including intelligence, self-efficacy, personality, well-being, and behavior problems. The mean of GCSE core subjects (English, mathematics, science) is more heritable (62%) than the nine predictor domains (35–58%). Each of the domains correlates significantly with GCSE results, and these correlations are largely mediated genetically. The main finding is that, although intelligence accounts for more of the heritability of GCSE than any other single domain, the other domains collectively account for about as much GCSE heritability as intelligence. Together with intelligence, these domains account for 75% of the heritability of GCSE. We conclude that the high heritability of educational achievement reflects many genetically influenced traits, not just intelligence….

Here is the press release from King’s College:

News
Why is educational achievement heritable?
Posted on 06/10/2014
Exams
New research, led by King’s College London finds that the high heritability of exam grades reflects many genetically influenced traits such as personality, behaviour problems, and self-efficacy and not just intelligence.
The study, published today in the Proceedings of the National Academy of Sciences (PNAS), looked at 13,306 twins at age 16 who were part of the Medical Research Council (MRC) funded UK TEDS | The Twins Early Development Study (TEDS). The twins were assessed on a range of cognitive and non-cognitive measures, and the researchers had access to their GCSE (General Certificate of Secondary Education) scores.
In total, 83 scales were condensed into nine domains: intelligence, self-efficacy (confidence in one’s own academic ability), personality, well-being, home environment, school environment, health, parent-reported behaviour problems and child reported behaviour problems.
Identical twins share 100% of their genes, and non-identical twins (just as any other siblings) share 50% of the genes that vary between people. Twin pairs share the same environment (family, schools, teachers etc). By comparing identical and non-identical twins, the researchers were able to estimate the relative contributions of genetic and environmental factors. So, if overall, identical twins are more similar on a particular trait than non-identical twins, the differences between the two groups are due to genetics, rather than environment.
Eva Krapohl, joint first author of the study, from the MRC Social, Genetic and Developmental Psychiatry (SGDP) Centre at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s, says: “Previous work has already established that educational achievement is heritable. In this study, we wanted to find out why that is. What our study shows is that the heritability of educational achievement is much more than just intelligence – it is the combination of many traits which are all heritable to different extents.
“It is important to point out that heritability does not mean that anything is set in stone. It simply means that children differ in how easy and enjoyable they find learning and that much of these differences are influenced by genetics.”
The researchers found that the heritability of GCSE scores was 62%. Individual traits were between 35% and 58% heritable, with intelligence being the most highly heritable. Together, the nine domains accounted for 75% of the heritability of GCSE scores.
Heritability is a population statistic which does not provide any information at an individual level. It describes the extent to which differences between children can be ascribed to DNA differences, on average, in a particular population at a particular time.
Kaili Rimfeld, joint-lead author, also from the IoPPN at King’s says: “No policy implications necessarily follow from finding that genetics differences influence educational achievement, because policy depends on values and knowledge. However, our findings support the idea that a more personalized approach to learning may be more successful than a one size fits all approach. Finding that educational achievement is heritable certainly does not mean that teachers, parents or schools aren’t important. Education is more than what happens to a child passively; children are active participants in selecting, modifying, and creating their experiences – much of which is linked to their genetic propensities, known in genetics as genotype–environment correlation.”
TEDS is supported by the UK Medical Research Council with additional funding from the National Institutes of Health.
Paper reference: Krapohl, E. et al. “The high heritability of educational achievement reflects many genetically influenced traits, not just intelligence” published in PNAS.
For further information, please contact Seil Collins, Press Officer, Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London seil.collins@kcl.ac.uk / (+44) 0207 848 5377

Teachers and schools have been made TOTALLY responsible for the education outcome of the children, many of whom come to school not ready to learn and who reside in families that for a variety of reasons cannot support their education. All children are capable of learning, but a one-size-fits-all approach does not serve all children well. Different populations of children will require different strategies and some children will require remedial help, early intervention, and family support to achieve their education goals. https://drwilda.com/2012/02/11/3rd-world-america-money-changes-everything/

ALL children have a right to a good basic education.

Resources:
The Global Creativity Index http://www.theatlanticcities.com/jobs-and-economy/2011/10/global-creativity-index/229/

The Rise of the Creative Class
http://www.washingtonmonthly.com/features/2001/0205.florida.html

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