Archive | November, 2019

Elsevier study: At what point does click-bait susceptibility become a mental health disorder?

17 Nov

Shahram Heshmat Ph.D. wrote in the Psychology Today article, 5 Patterns of Compulsive Buying: How do you know you have an addiction?

About 6% of the U.S. population can be said to have compulsive buying behavior with 80% of compulsive buyers being women. Many women have been socialized from a very young age to enjoy shopping with their mothers and friends (Workman & Paper, 2010). However, compulsive buying is likely to increase for men with the evolution of digital commerce. It is much faster and easier now to find what you are looking for.
Compulsive buying is similar to behavioral addiction, such as binge eating and gambling (Lawrence et al., 2014). Compulsive spending frequently co-occurs with other mental illnesses like depression, anxiety, and eating disorders. Unlike other addictions, which take hold in the teens, spending addictions mostly develop in the 30s when people achieve financial independence.
Compulsive buying is not listed as an addiction in the DSM-5. However, the impulse problem appears to share certain characteristics common in addictive disorders (Black, 2012).
1. Impulse purchase. Compulsive buyers often purchase things on impulse that they can do without. And they often try to conceal their shopping habits…. Compulsive buyers may develop into hoarders later in life after their products have accumulated with time (Mueller, 2007).
2. Buyers high. Compulsive shoppers experience a rush of excitement when they buy. The euphoric experience is not from owning something but from the act of buying it…. And this excitement can become addictive.
3. Shopping to dampen unpleasant emotions. Compulsive shopping is an attempt to fill an emotional void, like loneliness, lack of control, or lack of self-esteem. Often, a negative mood, such as an argument or frustration triggers an urge to shop. However, the decrease in negative emotions is temporary and it is replaced by an increase in anxiety or guilt (Donnelly et al., 2016).
4. Guilt and remorse. Purchases are followed by feelings of remorse. They feel guilty and irresponsible for purchases that they perceive as indulges. The result may be a vicious cycle, that is, negative feeling fuel another “fix,” purchasing something else.
5. The pain of paying. Paying with cash is more painful than paying with credit cards (Ariely and Kreisler, 2017). The main psychological force of credit cards is that they separate the pleasure of buying from the pain of paying. Credit cards seduce us into thinking about the positive aspects of a purchase. In fact, CBD is only prevalent in developed countries where there is a system of credit and a consumer culture. https://www.psychologytoday.com/intl/blog/science-choice/201806/5-patterns-compulsive-buying

See, Compulsive Shopping https://www.investopedia.com/terms/c/compulsive-shopping.asp and Compulsive Spending / Shopping https://www.goodtherapy.org/learn-about-therapy/issues/compulsive-shopping

Science Daily reported the Elsevier study: At what point does click-bait susceptibility become a mental health disorder?

A new study in Comprehensive Psychiatry, published by Elsevier, found that one third of a group of patients seeking treatment for buying-shopping disorder (BSD) also reported symptoms of addictive online shopping. These patients tended to be younger than the others in the study sample, experienced greater levels of anxiety and depression, and were likely to exhibit a higher severity of BSD symptoms.
“It really is time to recognize BSD as separate mental health condition and to accumulate further knowledge about BSD on the Internet,” explained lead investigator Astrid Müller, MD, PhD, Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hannover, Germany. At present, BSD is not categorized as a separate mental health condition; it is characterized as “other specified impulse control disorder” in the recently released 11th revision of the International Classification of Diseases.
BSD is a cross-national problem that afflicts an estimated five percent of the population. It is characterized by extreme preoccupation with and craving for buying and/or shopping, as well as irresistible and identity-seeking urges to possess consumer goods. Patients with BSD buy more consumer goods than they can afford, need, or use. Their excessive purchasing serves to regulate emotions, e.g., to get pleasure, relief from negative feelings or cope with self-discrepancy. In the long run, the recurrent breakdown in self-control leads to extreme distress, psychiatric comorbidity, familial discord, clutter due to pathological hoarding of goods, and indebtedness and/or deception and embezzlement to enable continued spending despite insufficient finances.
As e-commerce has gained increasing popularity as a primary method for buying and shopping for goods over the past decade, a need has developed for mental health experts to explore whether traditional BSD manifests differently in the online retail market. The Internet offers a vast variety of shopping information and simultaneous access to many online stores, thereby meeting expectations for immediate reward, emotional enhancement, and identity gain.
Previous studies showed that certain Internet-specific aspects of buying and shopping, such as availability, anonymity, accessibility, and affordability, contribute to the development of an online subtype of BSD. However, there is a paucity of studies investigating addictive online shopping as a phenotype of BSD related to the problematic use of the Internet. This study, which analyzed data from earlier studies reporting on 122 treatment-seeking patients, is among the first to quantify and explore the phenomenon of online shopping in BSD diagnosed-patients…. https://www.sciencedaily.com/releases/2019/11/191114100911.htm

Citation:

At what point does click-bait susceptibility become a mental health disorder?
Date: November 14, 2019
Source: Elsevier
Summary:
A new study found that one third of a group of patients seeking treatment for buying-shopping disorder (BSD) also reported symptoms of addictive online shopping. These patients tended to be younger than the others in the study sample, experienced greater levels of anxiety and depression, and were likely to exhibit a higher severity of BSD symptoms.
Journal Reference:
Astrid Müller, Sabine Steins-Loeber, Patrick Trotzke, Birte Vogel, Ekaterini Georgiadou, Martina de Zwaan. Online shopping in treatment-seeking patients with buying-shopping disorder. Comprehensive Psychiatry, 2019; 94: 152120 DOI: 10.1016/j.comppsych.2019.152120

Here is the press release from Elsevier:

At what point does click-bait susceptibility become a mental health disorder?
One third of patients seeking treatment for buying-shopping disorder report symptoms of online shopping addiction, according to a new study published in Comprehensive Psychiatry

Philadelphia, November 13, 2019
A new study in Comprehensive Psychiatry, published by Elsevier, found that one third of a group of patients seeking treatment for buying-shopping disorder (BSD) also reported symptoms of addictive online shopping. These patients tended to be younger than the others in the study sample, experienced greater levels of anxiety and depression, and were likely to exhibit a higher severity of BSD symptoms.
“It really is time to recognize BSD as separate mental health condition and to accumulate further knowledge about BSD on the Internet,” explained lead investigator Astrid Müller, MD, PhD, Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hannover, Germany. At present, BSD is not categorized as a separate mental health condition; it is characterized as “other specified impulse control disorder” in the recently released 11th revision of the International Classification of Diseases.
BSD is a cross-national problem that afflicts an estimated five percent of the population. It is characterized by extreme preoccupation with and craving for buying and/or shopping, as well as irresistible and identity-seeking urges to possess consumer goods. Patients with BSD buy more consumer goods than they can afford, need, or use. Their excessive purchasing serves to regulate emotions (e.g., to get pleasure, relief from negative feelings or cope with self-discrepancy). In the long run, the recurrent breakdown in self-control leads to extreme distress, psychiatric comorbidity, familial discord, clutter due to pathological hoarding of goods, and indebtedness and/or deception and embezzlement to enable continued spending despite insufficient finances.
As e-commerce has gained increasing popularity as a primary method for buying and shopping for goods over the past decade, a need has developed for mental health experts to explore whether traditional BSD manifests differently in the online retail market. The Internet offers a vast variety of shopping information and simultaneous access to many online stores, thereby meeting expectations for immediate reward, emotional enhancement, and identity gain.
Previous studies showed that certain Internet-specific aspects of buying and shopping, such as availability, anonymity, accessibility, and affordability, contribute to the development of an online subtype of BSD. However, there is a paucity of studies investigating addictive online shopping as a phenotype of BSD related to the problematic use of the Internet. This study, which analyzed data from earlier studies reporting on 122 treatment-seeking patients, is among the first to quantify and explore the phenomenon of online shopping in BSD diagnosed-patients.
Dr. Müller added, “We hope that our results showing that the prevalence of addictive online shopping among treatment-seeking patients with BSD will encourage future research addressing the distinct phenomenological characteristics, underlying features, associated comorbidity, and specific treatment concepts.”
Notes for editors
The article is “Online shopping in treatment-seeking patients with buying-shopping disorder,”by Astrid Müller, Sabine Steins-Loeber, Patrick Trotzke, Birte Vogel, Ekaterini Georgiadou, and Martina de Zwaan (https://doi.org/10.1016/j.comppsych.2019.152120). It appears in Comprehensive Psychiatry, volume 94 published by Elsevier.
This study is published open access and can be downloaded by following the DOI link above.
Full text of the article is available to credentialed journalists upon request. Contact Eileen Leahy at +1 732 238 3628or hmsmedia@elsevier.com to obtain copies. Journalists wishing to speak to the authors should contact Astrid Müller at mueller.astrid@mh-hannover.de.
About Comprehensive Psychiatry
Comprehensive Psychiatry is an open access, peer-reviewed journal that publishes on all aspects of psychiatry and mental health with a mission to disseminate cutting-edge knowledge in order to improve patient care and advance the understanding of mental illness. The Journal aims to publish high quality papers with a particular emphasis on the clinical implications of the work including an improved understanding of psychopathology.
About Elsevier
Elsevier is a global information analytics business that helps scientists and clinicians to find new answers, reshape human knowledge, and tackle the most urgent human crises. For 140 years, we have partnered with the research world to curate and verify scientific knowledge. Today, we’re committed to bringing that rigor to a new generation of platforms. Elsevier provides digital solutions and tools in the areas of strategic research management, R&D performance, clinical decision support, and professional education; including ScienceDirect, Scopus, SciVal, ClinicalKey and Sherpath. Elsevier publishes over 2,500 digitized journals, including The Lancet and Cell, 39,000 e-book titles and many iconic reference works, including Gray’s Anatomy. Elsevier is part of RELX, a global provider of information-based analytics and decision tools for professional and business customers. http://www.elsevier.com
Media contact
Eileen Leahy
Elsevier
+1 732 238 3628
hmsmedia@elsevier.com

Dr. April Benson wrote in Compulsive Shopping Treatment Overview:

As with most other addictive, impulse control, or compulsive disorders, there is a wide range of effective treatment options: drug treatment, individual, group, and couples therapy, counseling for compulsive buying, Debtors Anonymous, and Simplicity Circles can all be effective. The choice of what form or forms of compulsive shopping treatment to use with a particular person is a complex decision that goes well beyond the scope of this overview. For further information about making treatment decisions, consult my own writings, the For Therapists page of this website, as well as the bibliographic references at the end of each chapter in I Shop, Therefore I Am: Compulsive Buying and the Search for Self.
Psychotropic medications, including antidepressants, mood stabilizers, and opiod antagonists have been used to treat compulsive buying, with varying effectiveness. For further details, see McElroy and Goldsmith-Chapter 10 of I Shop, Therefore I Am and in Benson, April L. and Gengler, Marie. “Treatment of Compulsive Buying,” in Handbook of Addictive Disorders: A Practical Guide to Diagnosis and Treatment Handbook, Robert Coombs, (ed.), Wiley (2004).
Group therapy for compulsive buyers has been reported since the late 1980s. At least five different forms of group therapy have been utilized with this population. My own group compulsive shopping treatment model is an amalgam of three things: useful techniques from existing models; didactic and experiential material used in group treatment for Borderline Personality Disorder; and material I’ve found effective in my clinical practice. A study of the efficacy of this model has been submitted for publication to the Journal of Groups in Addiction and Recovery and two additional papers, one about the model itself, and the second, a case illustration of the model, will appear in Volume 8, Number 1, of the Journal of Groups in Addiction and Recovery (2013).
There are chapters about two of the existing group therapy models in my book, I Shop, Therefore I Am and I describe all five in detail in Benson, April L. and Gengler, Marie. “Treatment of Compulsive Buying,” in Handbook of Addictive Disorders: A Practical Guide to Diagnosis and Treatment Handbook, Robert Coombs, (ed.), Wiley (2004).
Couples therapy for compulsive buying is an extremely important treatment modality, because couples act as a financial unit and generally blend income as well as spending. Money issues are an intrinsic part of marriage and are often a source of intense and pervasive friction that can seep into other aspects of the relationship. Couples therapy is indicated when the compulsive spending problem can’t be dealt with adequately on an individual basis. Olivia Mellan, the country’s foremost expert in this area, discusses the treatment in Chapter 15, “Overcoming Overspending in Couples”, of I Shop, Therefore I Am.
How Does Compulsive Shopping Treatment Work?
Compulsive shopping treatment targets the specific problem and creates an action plan to stop the behavior. Targeted counseling for this problem alters the negative actions of compulsive buying and concurrently works toward healing the underlying emotions, although less emphasis is placed on exploring the emotional significance of compulsive buying than in traditional individual psychotherapy. The major premise of compulsive shopping treatment is the idea that insight alone will not stop the behavior. All stages in the compulsive buying cycle must be identified: the triggers, the feelings, the dysfunctional thoughts, the behaviors, the consequences of the behavior, as well as the meaning of the compulsive buying. Creating and using a spending plan is a cornerstone of compulsive shopping treatment. More information about compulsive buying counseling can be found in Karen McCall’s chapter “Financial Recovery Counseling”, as well as in my treatment chapter in Handbook of Addictive Disorders: A Practical Guide to Diagnosis and Treatment Handbook, Robert Coombs, (ed.), Wiley (2004).
Debtors Anonymous (D.A.) can be a powerful tool in recovery from compulsive buying, especially for compulsive buyers who have problems with debt. D.A. sees debting as a disease similar to alcoholism that can be cured with solvency, which means abstinence from any new debt. Since individuals are trying to control their lives with addictive debting, D.A. offers a regimented program of surrender and recovery, a program with a spiritual emphasis. Individual debtors work through the steps of the program with a sponsor, a more experienced member of the group, using newly acquired tools in conjunction with the steps. How Debtors Anonymous and psychotherapy can work synergistically is the topic of Kellen and Levine’s chapter of I Shop, Therefore I Am….. https://www.shopaholicnomore.com/complusive-shopping-treatment/

Your success and happiness lies in you. Resolve to keep happy, and your joy and you shall form an invincible host against difficulties.
Helen Keller

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Cincinnati Children’s Hospital Medical Center study: Screen-based media associated with structural differences in brains of young children

10 Nov

Andrew Stevensen wrote in the Sydney Morning Herald article, The screens that are stealing childhood:

Australians have smartphones and tablet computers gripped in their sweaty embrace, adopting the new internet-enabled technology as the standard operating platform for their lives, at work, home and play.
But it is not only adults who are on the iWay to permanent connection. As parents readily testify, many children don’t just use the devices, they are consumed by them.
”These devices have an almost obsessive pull towards them,” says Larry Rosen, professor of psychology at California State University and author of iDisorder: Understanding Our Obsession with Technology and Overcoming its Hold on Us.
”How can you expect the world to compete with something like an iPad3 with a high-definition screen, clear video and lots of interactivity? How can anything compete with that? There’s certainly no toy that can.
”Even old people like me can’t stop themselves from tapping their pocket to make sure their iPhone is there. Imagine a teenager, even a pre-teen, who’s grown up with these devices attached at the hip 24/7 and you end up with what I think is a problem.”
The technology has been absorbed so comprehensively that the jury on the potential impact on young people is not just out, it’s yet to be empanelled.
”The million-dollar question is whether there are risks in the transfer of real time to online time and the answer is that we just don’t know,” says Andrew Campbell, a child and adolescent psychologist….
Authoritative standards on appropriate levels of use are limited. The American Academy of Paediatrics recommends parents discourage TV for children under two and limit screen time for older children to less than two hours a day.
The guidelines, says Professor Rosen, are ”ludicrous” but the need for them and constant communication with young people about technology and how they use it, remains. ”It’s no longer OK to start talking to your kids about technology when they’re in their teens. You have to start talking to them about it as soon as you hand them your iPhone or let them watch television or Skype with grandma,” he says.
He suggests a ratio of screen time to other activities of 1:5 for very young children, 1:1 for pre-teens and 5:1 for teenagers. Parents should have weekly talks with their children from the start, looking for signs of obsession, addiction and lack of attention. http://www.smh.com.au/technology/technology-news/the-screens-that-are-stealing-childhood-20120528-1zffr.html

See, Technology Could Lead to Overstimulation in Kids http://www.educationnews.org/parenting/technology-could-lead-to-overstimulation-in-kids/

Science Daily reported in Screen-based media associated with structural differences in brains of young children:

A new study documents structural differences in the brains of preschool-age children related to screen-based media use.
The study, published in JAMA Pediatrics, shows that children who have more screen time have lower structural integrity of white matter tracts in parts of the brain that support language and other emergent literacy skills. These skills include imagery and executive function — the process involving mental control and self-regulation. These children also have lower scores on language and literacy measures.
The Cincinnati Children’s Hospital Medical Center study assessed screen time in terms of American Academy of Pediatrics (AAP) recommendations. The AAP recommendations not only take into account time spent in front of screens but also access to screens, including portable devices; content; and who children are with and how they interact when they are looking at screens.
“This study raises questions as to whether at least some aspects of screen-based media use in early childhood may provide sub-optimal stimulation during this rapid, formative state of brain development,” says John Hutton, MD, director of the, Reading & Literacy Discovery Center at Cincinnati Children’s and lead author of the study. “While we can’t yet determine whether screen time causes these structural changes or implies long-term neurodevelopmental risks, these findings warrant further study to understand what they mean and how to set appropriate limits on technology use….” https://www.sciencedaily.com/releases/2019/11/191104112918.htm

Citation:

Screen-based media associated with structural differences in brains of young children
Date: November 4, 2019
Source: Cincinnati Children’s Hospital Medical Center
Summary:
A new study documents structural differences in the brains of preschool-age children related to screen-based media use.

Journal Reference:
John S. Hutton, Jonathan Dudley, Tzipi Horowitz-Kraus, Tom DeWitt, Scott K. Holland. Associations Between Screen-Based Media Use and Brain White Matter Integrity in Preschool-Aged Children. JAMA Pediatrics, 2019; e193869 DOI: 10.1001/jamapediatrics.2019.3869

Here is the press release from Cincinnati Children’s Hospital Medical Center:

Screen-based media associated with structural differences in brains of young children
by Cincinnati Children’s Hospital Medical Center

The study, published in JAMA Pediatrics, shows that children who have more screen time have lower structural integrity of white matter tracts in parts of the brain that support language and other emergent literacy skills. These skills include imagery and executive function—the process involving mental control and self-regulation. These children also have lower scores on language and literacy measures.
The Cincinnati Children’s Hospital Medical Center study assessed screen time in terms of American Academy of Pediatrics (AAP) recommendations. The AAP recommendations not only take into account time spent in front of screens but also access to screens, including portable devices; content; and who children are with and how they interact when they are looking at screens.
“This study raises questions as to whether at least some aspects of screen-based media use in early childhood may provide sub-optimal stimulation during this rapid, formative state of brain development,” says John Hutton, MD, director of the, Reading & Literacy Discovery Center at Cincinnati Children’s and lead author of the study. “While we can’t yet determine whether screen time causes these structural changes or implies long-term neurodevelopmental risks, these findings warrant further study to understand what they mean and how to set appropriate limits on technology use.”
Among the AAP recommendations:
• For children younger than 18 months, avoid use of screen media other than video-chatting. Parents of children 18 to 24 months of age who want to introduce digital media should choose high-quality programming, and watch it with their children to help them understand what they’re seeing.
• For children ages 2 to 5 years, limit screen use to 1 hour per day of high-quality programs. Parents should co-view media with children to help them understand what they are seeing and apply it to the world around them.
• Designate media-free times together, such as dinner or driving, as well as media-free locations at home, such as bedrooms.
• Higher ScreenQ scores were associated with lower brain white matter integrity, which affects organization and myelination—the process of forming a myelin sheath around a nerve to allow nerve impulses to move more quickly—in tracts involving language executive function and other literacy skills.
“Screen-based media use is prevalent and increasing in home, childcare and school settings at ever younger ages,” says Dr. Hutton. “These findings highlight the need to understand effects of screen time on the brain, particularly during stages of dynamic brain development in early childhood, so that providers, policymakers and parents can set healthy limits.”
________________________________________
Explore further
New studies measure screen-based media use in children https://medicalxpress.com/news/2018-05-screen-based-media-children.html
________________________________________
Journal information: JAMA Pediatrics
Provided by Cincinnati Children’s Hospital Medical Center https://medicalxpress.com/news/2019-11-screen-based-media-differences-brains-young.html

There is something to be said for Cafe Society where people actually meet face-to-face for conversation or the custom of families eating at least one meal together. Time has a good article on The Magic of the Family Meal http://content.time.com/time/magazine/article/0,9171,1200760,00.html See, also Family Dinner: The Value of Sharing Meals http://www.ivillage.com/family-dinner-value-sharing-meals/6-a-128491
Perhaps, acting like the power is out from time to time and using Helen Robin’s suggestions is not such a bad idea.

Related:

Two studies: Social media and social dysfunction https://drwilda.com/2013/04/13/two-studies-social-media-and-social-dysfunction/

Common Sense Media report: Kids migrating away from Facebook
https://drwilda.com/tag/the-impact-of-social-media-use-on-children/

Is ‘texting’ destroying literacy skills https://drwilda.com/2012/07/30/is-texting-destroying-literacy-skills/

Where information leads to Hope. © Dr. Wilda.com

Dr. Wilda says this about that ©

Blogs by Dr. Wilda:

COMMENTS FROM AN OLD FART ©
http://drwildaoldfart.wordpress.com/

Dr. Wilda Reviews ©
http://drwildareviews.wordpress.com/

Dr. Wilda ©
https://drwilda.com/

Rensselaer Polytechnic Institute and Yale School of Medicine study: Living skin can now be 3D-printed with blood vessels included

2 Nov

Debra Stang wrote in the Heathline article, Skin Graft, which was Medically reviewed by Catherine Hannan, MD on May 30, 2017:

What is a skin graft?
Skin grafting is a surgical procedure that involves removing skin from one area of the body and moving it, or transplanting it, to a different area of the body. This surgery may be done if a part of your body has lost its protective covering of skin due to burns, injury, or illness.
Skin grafts are performed in a hospital. Most skin grafts are done using general anesthesia, which means you’ll be asleep throughout the procedure and won’t feel any pain.
Why are skin grafts done?
A skin graft is placed over an area of the body where skin has been lost. Common reasons for a skin graft include:
• skin infections
• deep burns
• large, open wounds
• bed sores or other ulcers on the skin that haven’t healed well
• skin cancer surgery
Types of skin grafts
There are two basic types of skin grafts: split-thickness and full-thickness grafts.
Split-thickness grafts
A split-thickness graft involves removing the top layer of the skin — the epidermis — as well as a portion of the deeper layer of the skin, called the dermis. These layers are taken from the donor site, which is the area where the healthy skin is located. Split-thickness skin grafts are usually harvested from the front or outer thigh, abdomen, buttocks, or back.
Split-thickness grafts are used to cover large areas. These grafts tend to be fragile and typically have a shiny or smooth appearance. They may also appear paler than the adjoining skin. Split-thickness grafts don’t grow as readily as ungrafted skin, so children who get them may need additional grafts as they grow older.
Full-thickness grafts
A full-thickness graft involves removing all of the epidermis and dermis from the donor site. These are usually taken from the abdomen, groin, forearm, or area above the clavicle (collarbone). They tend to be smaller pieces of skin, as the donor site from where it’s harvested is usually pulled together and closed in a straight-line incision with stitches or staples.
Full-thickness grafts are generally used for small wounds on highly visible parts of the body, such as the face. Unlike split-thickness grafts, full-thickness grafts blend in well with the skin around them and tend to have a better cosmetic outcome…. https://www.healthline.com/health/skin-graft#types
See, Skin Graft Ruka Shimizu and Kazuo Kishi* https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335647/
Tyler Lacoma wrote in What is 3D printing? Here’s everything you need to know:
3D printing is a manufacturing process that creates a three dimensional object by incrementally adding material until the object is complete (this contrasts with subtractive manufacturing techniques such as carving or milling, in which an object is created by selectively removing parts from a piece of raw material). A 3D printer is simply a machine that can take a digital 3D model and turn it into a tangible 3D object via additive manufacturing. While these printers come in many forms, they all have three basic parts….
It’s hard to find a sector that hasn’t been affected by 3D printing. Manufacturing processes around the world have adopted 3D printing techniques to help solve their problems and improve efficiency. When used in mass production, 3D printing tends to be cheaper than any other method. When used to create prototypes, it’s typically the fastest option. But that’s just the beginning! Check just a few of the incredible ways that 3D printing is currently being used.
 Shoes: Companies like Feetz and 3D Shoes manufacture 3D-printed shoes on demand, with plenty of customization options. Bigger brands are getting into the business, too!
 Houses: Yes, we are printing 3D houses now, too! In fact, manufacturer Apis Ctor has developed a house that can be printed and painted in 24 hours.
 Healthcare materials: Common, disposable healthcare objectives, like sample cups, now often come from 3D printing systems. In the prosthetics world, 3D printing is used to create customized prosthetics for individual’s unique bodies and requirements. Advanced systems are even creating 3D skin grafts made out of biological ink.
 Custom ordering: At home or work and feeling left out of the 3D printing business? Thousands of printing companies now offer 3D printing where you specify objects, materials, and place your order online.
 Set Design: Set design and prop-making have fully embraced 3D printing as a far cheaper, faster way to create very specific props for today’s shows and theater. Think how much easier it is to create an alien environment when you can draw, program, and print a usable version of even the most outlandish or historical objects in no time at all! https://www.digitaltrends.com/computing/what-is-3d-printing/

Resources:

Medical Applications of 3D Printing https://www.fda.gov/medical-devices/3d-printing-medical-devices/medical-applications-3d-printing
3D printing in medicine: How the technology is increasingly being used to save lives https://binged.it/2WJ7WsA

3D Printing in Medicine: The Best Applications in 2019                                https://all3dp.com/2/3d-printing-in-medicine-the-best-applications/

Science Daily reported the Rensselaer Polytechnic Institute study: Living skin can now be 3D-printed with blood vessels included

Researchers at Rensselaer Polytechnic Institute have developed a way to 3D print living skin, complete with blood vessels. The advancement, published online today in Tissue Engineering Part A, is a significant step toward creating grafts that are more like the skin our bodies produce naturally.
“Right now, whatever is available as a clinical product is more like a fancy Band-Aid,” said Pankaj Karande, an associate professor of chemical and biological engineering and member of the Center for Biotechnology and Interdisciplinary Studies (CBIS), who led this research at Rensselaer. “It provides some accelerated wound healing, but eventually it just falls off; it never really integrates with the host cells.”
A significant barrier to that integration has been the absence of a functioning vascular system in the skin grafts.
Karande has been working on this challenge for several years, previously publishing one of the first papers showing that researchers could take two types of living human cells, make them into “bio-inks,” and print them into a skin-like structure. Since then, he and his team have been working with researchers from Yale School of Medicine to incorporate vasculature.
In this paper, the researchers show that if they add key elements — including human endothelial cells, which line the inside of blood vessels, and human pericyte cells, which wrap around the endothelial cells — with animal collagen and other structural cells typically found in a skin graft, the cells start communicating and forming a biologically relevant vascular structure within the span of a few weeks. You can watch Karande explain this development here.
“As engineers working to recreate biology, we’ve always appreciated and been aware of the fact that biology is far more complex than the simple systems we make in the lab,” Karande said. “We were pleasantly surprised to find that, once we start approaching that complexity, biology takes over and starts getting closer and closer to what exists in nature.”
Once the Yale team grafted it onto a special type of mouse, the vessels from the skin printed by the Rensselaer team began to communicate and connect with the mouse’s own vessels.
“That’s extremely important, because we know there is actually a transfer of blood and nutrients to the graft which is keeping the graft alive,” Karande said.
In order to make this usable at a clinical level, researchers need to be able to edit the donor cells using something like the CRISPR technology, so that the vessels can integrate and be accepted by the patient’s body.
“We are still not at that step, but we are one step closer,” Karande said.
“This significant development highlights the vast potential of 3D bioprinting in precision medicine, where solutions can be tailored to specific situations and eventually to individuals,” said Deepak Vashishth, the director CBIS. “This is a perfect example of how engineers at Rensselaer are solving challenges related to human health….” https://www.sciencedaily.com/releases/2019/11/191101111556.htm

Citation:

Living skin can now be 3D-printed with blood vessels included
Development is significant step toward skin grafts that can be integrated into patient’s skin
Date: November 1, 2019
Source: Rensselaer Polytechnic Institute
Summary:
Researchers have developed a way to 3D print living skin, complete with blood vessels. The advancement is a significant step toward creating grafts that are more like the skin our bodies produce naturally.

Journal Reference:
Tânia Baltazar, Jonathan Merola, Carolina Motter Catarino, Catherine Bingchan Xie, Nancy Kirkiles-Smith, Vivian Lee, Stéphanie Yuki Kolbeck Hotta, Guohao Dai, Xiaowei Xu, Frederico Castelo Ferreira, W Mark Saltzman, Jordan S Pober, Pankaj Karande. 3D bioprinting of a vascularized and perfusable skin graft using human keratinocytes, (..). Tissue Engineering Part A, 2019; DOI: 10.1089/ten.TEA.2019.0201

Here is the press release from Rensselaer Polytechnic Institute:

November 1, 2019
Living Skin Can Now be 3D-Printed With Blood Vessels Included
Development is significant step toward skin grafts that can be integrated into patient’s skin

TROY, N.Y. — Researchers at Rensselaer Polytechnic Institute have developed a way to 3D print living skin, complete with blood vessels. The advancement, published online today in Tissue Engineering Part A, is a significant step toward creating grafts that are more like the skin our bodies produce naturally.
“Right now, whatever is available as a clinical product is more like a fancy Band-Aid,” said Pankaj Karande, an associate professor of chemical and biological engineering and member of the Center for Biotechnology and Interdisciplinary Studies (CBIS), who led this research at Rensselaer. “It provides some accelerated wound healing, but eventually it just falls off; it never really integrates with the host cells.”
A significant barrier to that integration has been the absence of a functioning vascular system in the skin grafts.
Karande has been working on this challenge for several years, previously publishing one of the first papers showing that researchers could take two types of living human cells, make them into “bio-inks,” and print them into a skin-like structure. Since then, he and his team have been working with researchers from Yale School of Medicine to incorporate vasculature.
In this paper, the researchers show that if they add key elements — including human endothelial cells, which line the inside of blood vessels, and human pericyte cells, which wrap around the endothelial cells — with animal collagen and other structural cells typically found in a skin graft, the cells start communicating and forming a biologically relevant vascular structure within the span of a few weeks.
Watch Karande explain this development:
“As engineers working to recreate biology, we’ve always appreciated and been aware of the fact that biology is far more complex than the simple systems we make in the lab,” Karande said. “We were pleasantly surprised to find that, once we start approaching that complexity, biology takes over and starts getting closer and closer to what exists in nature.”
Once the Yale team grafted it onto a special type of mouse, the vessels from the skin printed by the Rensselaer team began to communicate and connect with the mouse’s own vessels.
“That’s extremely important, because we know there is actually a transfer of blood and nutrients to the graft which is keeping the graft alive,” Karande said.
In order to make this usable at a clinical level, researchers need to be able to edit the donor cells using something like the CRISPR technology, so that the vessels can integrate and be accepted by the patient’s body.
“We are still not at that step, but we are one step closer,” Karande said.
“This significant development highlights the vast potential of 3D bioprinting in precision medicine, where solutions can be tailored to specific situations and eventually to individuals,” said Deepak Vashishth, the director CBIS. “This is a perfect example of how engineers at Rensselaer are solving challenges related to human health.”
Karande said more work will need to be done to address the challenges associated with burn patients, which include the loss of nerve and vascular endings. But the grafts his team has created bring researchers closer to helping people with more discrete issues, like diabetic or pressure ulcers.
“For those patients, these would be perfect, because ulcers usually appear at distinct locations on the body and can be addressed with smaller pieces of skin,” Karande said. “Wound healing typically takes longer in diabetic patients, and this could also help to accelerate that process.”
At Rensselaer, Karande’s team also includes Carolina Catarino, doctoral student in chemical and biological engineering. The Yale team includes Tania Baltazar, a postdoctoral researcher who previously worked on this project at Rensselaer; Dr. Jordan Pober, a professor of immunobiology; and Mark Saltzman, a professor of biomedical engineering.
This work was supported by a grant from the National Institutes of Health.
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ABOUT RENSSELAER POLYTECHNIC INSTITUTE
Founded in 1824, Rensselaer Polytechnic Institute is America’s first technological research university. Rensselaer encompasses five schools, 32 research centers, more than 145 academic programs, and a dynamic community made up of more than 7,900 students and more than 100,000 living alumni. Rensselaer faculty and alumni include more than 145 National Academy members, six members of the National Inventors Hall of Fame, six National Medal of Technology winners, five National Medal of Science winners, and a Nobel Prize winner in Physics. With nearly 200 years of experience advancing scientific and technological knowledge, Rensselaer remains focused on addressing global challenges with a spirit of ingenuity and collaboration.

Jeff Kerns wrote in A Look at the Future of Medical 3D Printing, Part 1: Science fiction continues to become reality as 3D printing cuts deeper into the medical industry:

Available Soon
Unveiled at the Radiological Society of North America’s 2017 show, Stratasys unveiled 3D-printed anatomical structures, including disease pathologies that mimic the look and feel of biological parts to accelerate guidance, testing, and education. Engineered in conjunction with top researchers and manufacturers, service initially includes fully functional bone and heart models, with vascular structures expected in early 2018. This technology will eliminate restrictions associated with research on animal, mannequin, or cadaver models—BioMimics effectively mirrors intricacies of both soft tissue and hard bones via multi-material 3D printing.
These are only models, so regulations are fewer than if you were 3D printing the actual organs to go into a patient. While there are recently published reviews describing the use of 3D printing to produce bones, ears, windpipes, jawbones, cells, blood vessels, and more, it will take time before this technology is common practice. An estimate published by the U.S. National Library of Medicine National Institute of Health says that we are less than 20 years from a fully functioning printable heart.
However, it should be cautioned that despite recent significant and exciting medical advances involving 3D printing, notable scientific and regulatory challenges remain, and the most transformative applications for this technology will need time to evolve.
In our next installment, the future of 3D printing tissues, organs, and custom pharmaceuticals will be discussed. Many professionals say 3D printing is getting a lot of hype, but it will be a long time before we start seeing 3D-printed organs. However, the fact that they seem to be saying “It will take a long time,” and not “This will never happen,” is exciting enough. Also, the idea that we may see printed bone and tissue earlier than when organ printing was predicted make it hard not to justify the hype around this technology.
But for the time being, we’ll just need to keep eating right and exercising.
https://www.machinedesign.com/3d-printing/look-future-medical-3d-printing-part-1

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