European Society of Cardiology study: Higher coffee consumption associated with lower risk of early death

3 Sep

The Harvard Gazette reported in How coffee loves us back: Health benefits a recurring theme in Harvard research:

Coffee is everywhere, through history and across the world. And increasingly, science is demonstrating that its popularity is a good thing.
Harvard scientists have for years put coffee under the microscope. Last year, researchers announced they had discovered six new human genes related to coffee and reconfirmed the existence of two others. The long-running Nurses’ Health Study has found that coffee protects against type 2 diabetes and cardiovascular disease. Researchers are continuing to follow up on 2001 findings that it protects against Parkinson’s disease.
The work at Harvard is just part of an emerging picture of coffee as a potentially powerful elixir against a range of ailments, from cancer to cavities.
Sanjiv Chopra, a professor of medicine at Harvard Medical School and Harvard-affiliated Beth Israel Deaconess Medical Center, has been so impressed he’s become something of a coffee evangelist. The author of several books, Chopra included a chapter on coffee in his 2010 book, “Live Better, Live Longer.”
Chopra first became aware of the potentially powerful protective effects of coffee when a study revealed that consumption lowers levels of liver enzymes and protects the liver against cancer and cirrhosis. He began asking students, residents, and fellows on the liver unit to quiz patients about their coffee habits, finding repeatedly that none of the patients with liver ailments drank coffee.
Chopra himself makes sure to have several cups a day, and encourages others to do the same. Though other researchers are less bold in their dietary recommendations, they’re convinced enough to continue investigations into the benefits…. https://news.harvard.edu/gazette/story/2015/09/how-coffee-loves-us-back/

The Harvard research findings are described in Medical News.

Joseph Nordqvist reported in the Medical News article, Coffee: Health Benefits, Nutritional Information:

Possible health benefits of coffee
The potential health benefits associated with drinking coffee include: protecting against type 2 diabetes, Parkinson’s disease, liver disease, liver cancer, and promoting a healthy heart.3
1) Coffee and diabetes
Coffee may be protective against type 2 diabetes. Researchers at UCLA identified that drinking coffee increases plasma levels of the protein sex hormone-binding globulin (SHBG). SHBG controls the biological activity of the body’s sex hormones (testosterone and estrogen) which play a role in the development of type 2 diabetes.4
Dr. Simin Liu, one of the authors of the study, said that an “inverse association” exists between coffee consumption and risk for type 2 diabetes….
2) Coffee and Parkinson’s disease
Researchers in the U.S. carried out a study that assessed the link between coffee consumption and Parkinson’s disease risk. The authors of the study concluded that “higher coffee and caffeine intake is associated with a significantly lower incidence of Parkinson’s disease”.5
In addition, caffeine in coffee may help control movement in people suffering from Parkinson’s, according to a study conducted at the Research Institute of the McGill University Health Centre (RI MUHC) that was published in the journal Neurology.6
3) Coffee and liver cancer
Italian researchers found that coffee consumption lowers the risk of liver cancer by about 40%. In addition, some of the results suggest that if you drink three cups a day, the risks are reduced by more than 50%.7
The lead author of the study, Dr. Carlo La Vecchia, from Milan’s Istituto di Ricerche Farmacologiche Mario Negri, said “our research confirms past claims that coffee is good for your health and particularly the liver.”
4) Coffee and liver disease
Regular consumption of coffee is linked to a reduced risk of primary sclerosing cholangitis (PSC), a rare autoimmune disease of the bile ducts in the liver.8
In addition, coffee consumption can lower the incidence of cirrhosis of the liver for alcohol drinkers by 22%, according to a study at the Kaiser Permanente Medical Care Program, California, USA.
The authors of the study concluded that the results “support the hypothesis that there is an ingredient in coffee that protects against cirrhosis, especially alcoholic cirrhosis.”9
Research published in the journal Hepatology in April 2014, suggested that drinking coffee is linked to a decreased liver cirrhosis death risk. The researchers suggested that drinking two or more cups of coffee every day can reduce the risk of death from liver cirrhosis by 66%.16
A study published in the journal Hepatology indicates that drinking decaf coffee also lowers liver enzyme levels, suggesting the benefits are not linked to caffeine content.
5) Coffee and heart health
Researchers at Beth Israel Deaconess Medical Center (BIDMC) and Harvard School of Public Health, concluded that drinking coffee in moderation protects against heart failure. They defined ‘in moderation’ as 2 European cups (equivalent to two 8-ounce American servings) per day.10
People who drank four European cups on a daily basis had an 11% lower risk of heart failure, compared to those who did not.
The authors stressed that their results “did show a possible benefit, but like with so many other things we consume, it really depends on how much coffee you drink.”
Recent developments on the benefits of coffee from MNT news
Moderate coffee drinking may prevent premature death
Incredible volumes of black gold are poured into our collective bodies on a daily basis, which makes the medical effects of coffee drinking a perpetual area of study. Now, new research points to some interesting positive health benefits of moderate consumption.
Study provides more evidence that coffee may reduce mortality
A new study adds to growing evidence that coffee is good for us, finding that consuming four to five cups daily may reduce the risk of early death – even for those who drink decaf.
Coffee may protect against liver cirrhosis
Drinking coffee every day is linked to a reduced risk of liver cirrhosis, according to a new review of published evidence that also suggests drinking two extra cups a day may nearly halve the risk of dying from the disease.
Drinking more coffee may stave off multiple sclerosis
Research published in the Journal of Neurology, Neurosurgery and Psychiatry indicates that caffeine’s neuroprotective and anti-inflammatory properties may lower the risk of developing multiple sclerosis.
Daily coffee, even decaf, may protect against colorectal cancer
Researchers from the US and Israel found that drinking coffee every day – even decaffeinated coffee – may lower the risk of colorectal cancer.
http://www.medicalnewstoday.com/articles/270202.php

David DiSalvo wrote in the Forbes article, Drinking Coffee May Lower Risk Of Early Death, According To New Study:

A new study is adding to the good news about coffee, finding that drinking two to four cups a day is associated with overall lower risk of death, particularly among middle-age drinkers.
The findings, presented at the European Cardiac Society Congress 2017, are the result of a long-term observational study of nearly 20,000 people in Spain. The average age of participants was 37, and they were followed for about ten years. During that time, 337 participants died. The researchers found that participants who consumed at least four cups of coffee per day had a 64% lower risk of death than those who infrequently or never consumed coffee. They also found a 22% lower risk of death for participants who drank two cups a day.
Lower risk was especially strong for older participants, with two cups a day linked to a 30% reduction in mortality.
“We found an inverse association between drinking coffee and the risk of all-cause mortality, particularly in people aged 45 years and above. This may be due to a stronger protective association among older participants,” says Dr. Adela Navarro, study co-author and a cardiologist at Hospital de Navarra in Pamplona, Spain.
That’s the good news. The qualifier is that this was an observational study, and several other factors could come into play. The researchers report that they accounted for factors including age, sex and whether the participants predominantly ate a Mediterranean Diet, which has also been linked to a list of health benefits. The correlation between coffee consumption and lower risk of death appears to stand out, but it’s important to note that it’s a correlation – not proof of causation…. https://www.forbes.com/sites/daviddisalvo/2017/08/27/drinking-coffee-may-lower-risk-of-death-in-healthy-people-according-to-new-study/#7a1c1924f82a

Citation:

Higher coffee consumption associated with lower risk of early death
Date: August 27, 2017
Source: European Society of Cardiology
Summary:
Higher coffee consumption is associated with a lower risk of early death, according to new research. The observational study in nearly 20 000 participants suggests that coffee can be part of a healthy diet in healthy people.
https://www.sciencedaily.com/releases/2017/08/170827101750.htm

Here is the press release from the European Society of Cardiology:

Higher coffee consumption associated with lower risk of death
27 Aug 2017
Topic(s):
Prevention
Barcelona, Spain – 27 Aug 2017: Higher coffee consumption is associated with a lower risk of death, according to research presented today at ESC Congress.1 The observational study in nearly 20 000 participants suggests that coffee can be part of a healthy diet in healthy people.

“Coffee is one of the most widely consumed beverages around the world,” said Dr Adela Navarro, a cardiologist at Hospital de Navarra, Pamplona, Spain. “Previous studies have suggested that drinking coffee might be inversely associated with all-cause mortality but this has not been investigated in a Mediterranean country.”

The purpose of this study was to examine the association between coffee consumption and the risk of mortality in a middle-aged Mediterranean cohort. The study was conducted within the framework of the Seguimiento Universidad de Navarra (SUN) Project, a long-term prospective cohort study in more than 22 500 Spanish university graduates which started in 1999.

This analysis included 19 896 participants of the SUN Project, whose average age at enrolment was 37.7 years old. On entering the study, participants completed a previously validated semi-quantitative food frequency questionnaire to collect information on coffee consumption, lifestyle and sociodemographic characteristics, anthropometric measurements, and previous health conditions.

Patients were followed-up for an average of ten years. Information on mortality was obtained from study participants and their families, postal authorities, and the National Death Index. Cox regression models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for incident mortality according to baseline total coffee consumption adjusted for potential confounders.

During the ten year period, 337 participants died. The researchers found that participants who consumed at least four cups of coffee per day had a 64% lower risk of all-cause mortality than those who never or almost never consumed coffee (adjusted HR, 0.36; 95% CI, 0.19–0.70). There was a 22% lower risk of all-cause mortality for each two additional cups of coffee per day (adjusted HR, 0.78; 95% CI, 0.66–0.92).

The researchers examined whether sex, age or adherence to the Mediterranean diet had any influence on the association between baseline coffee consumption and mortality. They observed a significant interaction between coffee consumption and age (p for interaction=0.0016). In those who were at least 45 years old, drinking two additional cups of coffee per day was associated with a 30% lower risk of mortality during follow-up (adjusted HR, 0.70; 95% CI, 0.58–0.85). The association was not significant among younger participants.

Dr Navarro said: “In the SUN project we found an inverse association between drinking coffee and the risk of all-cause mortality, particularly in people aged 45 years and above. This may be due to a stronger protective association among older participants.”

She concluded: “Our findings suggest that drinking four cups of coffee each day can be part of a healthy diet in healthy people.”

ENDS
Notes to editor
Sources of funding: The SUN Project is funded by the Instituto de Salud Carlos III, the CIBER, and the Regional Government of Navarra.

References and notes
(1) The abstract “Coffee consumption and all-cause mortality in a Mediterranean cohort: the SUN project” will be presented during:
· The session Impact of traditional and novel lifestyle factors on cardiovascular disease on Sunday 27 August from 11:00 to 12:30 in Picasso – The Hub.
Disclosures: All authors declare they have no conflict of int

As with anything, coffee should be consumed in moderation.

Resources:

Online Courses for Coffee Professionals: Master roasting coffee, cupping, coffee quality evaluation and understand the path of the coffee from the farm to cup. https://bootcampcoffee.com/

Learn About Coffee http://www.coffeeteawarehouse.com/coffee.html

The NCA Complete Guide to Coffee
We believe that coffee is more than just a drink: It’s a culture, an economy, an art, a science — and a passion. Whether you’re new to the brew or an espresso expert, there’s always more to learn about this beloved beverage. http://www.ncausa.org/About-Coffee

coffeeresearch.org

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